| Objective:To analyze the relationship between urinary albumin excretion rate (UAER) and glomerular filtration rate
(eGFR) in patients with type 2 diabetes mellitus (T2DM) and explore the related risk factors.Methods:470 patients with type 2 diabetes
mellitus who were treated in our hospital were selected on the basis of the UAER and eGFR. Then the general information of patients was
collected, and the relationship between UAER and eGFR and related risk factors were analyzed.Results:There was statistically significant
difference about the body weight, body surface area, BMI, DBP, SBP, TG, TC, hypertension, serum creatinine and uric acid of patients
with different UAER (P<0.05). There was statistically significant difference about the age, body mass, diabetes duration, body surface
area, BMI, hypertension, HbA1c, HDL-C, serum creatinine and uric acid levels of patients with different eGFR (P<0.05). The incidence
rate of abnormal renal function was highest in patients with large quantity of albuminuria and lowest in patients with normal albuminuria,
and the difference was statistically significant (P<0.05). Patients of eGFR ≥ 90ml·min-1·1.73m-2 with normal, small amount of
and large quantity of albuminuria accounted for 82.08%, 13.68% and 4.25%, respectively. According to the cross validation analysis,
UAER and EGFR were correlated (P<0.05). Logistic regression analysis showed that the risk factors of UAER included serum creatinine,
systolic blood pressure and BMI, and the risk factors of eGFR were age, body mass and serum creatinine (P<0.05).Conclusion:There is
correlation between UAER and eGFR, and the combined detection should be conducive to early diagnosis of type 2 diabetic renal injury.
The related risk factors include serumcreatinine, systolic blood pressure and BMI. |
