| 季瑛 赵晓霞 刘世龙 王赟 贾慧珍.抗VEGF药物联合532 激光治疗视网膜中央静脉阻塞的疗效分析[J].,2016,16(23):4484-4486 |
| 抗VEGF药物联合532 激光治疗视网膜中央静脉阻塞的疗效分析 |
| Efficacy of Anti VEGF Drugs Combined with 532 Laser in Treatment ofCentral Retinal Vein Occlusion |
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| 中文关键词: 视网膜中央静脉阻塞 抗VEGF 药物 激光治疗 黄斑中心凹厚度 视力 |
| 英文关键词: Central retinal vein occlusion Anti-VEGF drugs Laser treatment CMT Vision |
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| 中文摘要: |
| 目的：探讨抗VEGF药物联合532 激光治疗视网膜中央静脉阻塞的疗效。方法：选取60 例患视网膜中央静脉阻塞患者，年
龄38-65 岁，研究组(31 例)采用抗VEGF药物联合532 激光治疗，对照组(29 例)单纯给予激光治疗。监测患者治疗前，治疗后3个
月的视力，黄斑中心凹厚度（Central macular thickness, CMT）以及治疗后3 个月的治疗结果，对联合治疗与单纯激光方式的疗效
进行对比。结果：治疗后3 个月，研究组有效率明显高于对照组(P＜0.05)。与治疗前相比，研究组治疗后3 个月，视力改善情况较明
显(P＜0.05)，且改善幅度大于对照组(P＜0.05)。对照组治疗后3 个月，视力有了小幅度改善，然而与治疗前相比，差异没有统计学
意义(P>0.05)。治疗前，两组CMT 相比，差异没有统计学意义(P>0.05)。治疗后3 个月，两组CMT 均有明显改善，且研究组改变情
况优于对照组(P＜0.05)。所有患者在治疗后3 个月内均未严重并发症。结论：抗VEGF药物联合532激光治疗视网膜中央静脉阻
塞，可以显著提高患者视力和治疗有效率，降低黄斑水肿，新生血管等并发症发生率，并且不会引起其他并发症。 |
| 英文摘要: |
| Objective:To discuss the efficacy of anti VEGF drugs combined with 532 laser in treatment of central retinal vein
occlusion.Methods:60 patients with central retinal vein occlusion, 38-65 years old were selected and divided into two groups. The study
group(31 cases) was given anti VEGF drugs combined with 532 laser, and the control group(29 cases) was adopted laser treatment. The
vision and central macular thickness before therapy and 3 months after therapy, and the therapeutic outcome after 3 months therapy was
observed. The efficacy of two different therapy were evaluated by these indexes.Results:After 3 months therapy, the rate of study group
was obviously higher than that of control group (P<0.05). Compared with the vision before therapy, the vision became better after 3
months therapy in the study group. Besides, the improvement range in the study group was higher than that of the control group (P<0.05).
After 3 months therapy, the vision of control group was improved, but there was no statistical significance between before and after
treatment (P>0.05). Before therapy, there was no statistical significance on CMT between two groups (P>0.05), after 3 months therapy,
the CMT in two groups was improved, and it was better in the study group (P<0.05). After therapy, no serious complications were
detected in 3 months.Conclusion:The anti-VEGF drugs combined with 532 laser in treatment of the central retinal vein occlusion can
significantly improve the vision of the patients, and obtain high effective rate and low accident rate of macular edema and
neovascularization. The other complications will not be caused by this method. |
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