| 张俊娟 徐丽娟 李玉珍 孟玲娟 叶盛前 张俊静.小儿重症肺炎红细胞体积分布宽度与患儿近期预后的相关性分析[J].,2016,16(22):4314-4317 |
| 小儿重症肺炎红细胞体积分布宽度与患儿近期预后的相关性分析 |
| Analysis on Correlation of Red Blood Cell Volume Distribution Width withRecent Prognosis of Children with Severe Pneumonia |
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| DOI： |
| 中文关键词: 红细胞分布宽度 重症肺炎 预后 |
| 英文关键词: Red blood cell distribution width Severe pneumonia Prognosis |
| 基金项目:河北省卫生厅科研项目（20130080） |
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| 中文摘要: |
| 目的：探讨小儿重症肺炎红细胞体积分布宽度(RDW)与患儿近期预后的相关性。方法：选择107 例重症肺炎患儿为研究对
象，检测患儿入院时RDW水平，记录相关实验室检查指标及住院后28d 的转归情况，将患者分为死亡组和存活组，高RDW 组和
正常RDW组，分析各组之间相关指标的差异，并探讨RDW与患儿近期预后的关系。结果：死亡组患儿的入院急性病生理学和长
期健康评价评分Ⅱ(APACHEⅡ)评分、降钙素原(PCT)、超敏C- 反应蛋白(hs-CRP)、白细胞计数(WBC)、中性粒细胞百分比(PMN)、
血沉(ESR)高于存活组(P＜0.05)，RDW水平亦高于存活组(P＜0.05)；高RDW组患儿APACHEⅡ评分、PCT、hs-CRP、WBC、PMN、
ESR 高于正常RDW组，死亡率亦高于正常RDW组(P＜0.05)。Logistic回归分析显示RDW水平是重症肺炎患儿近期死亡的独立
危险因素(OR=2.025，95%CI:1.252～4.243,P＜0.05）；ROC 曲线分析显示：RDW 水平预测重症肺炎患儿死亡的ROCAUC 为
0.801，灵敏度为82.0，特异度为74.4，最佳诊断截点为16.35%。结论：RDW水平可能是重症肺炎患儿近期预后不良的独立危险因
素，并对患儿预后可能具有较好的预测价值。 |
| 英文摘要: |
| Objective:To investigate the correlation of red blood cell volume distribution width (RDW) with the recent prognosis
of children with severe pneumonia.Methods:Selected 107 cases of children with severe pneumonia as the research object. Detected the
RDWlevel on admission, and recorded the related laboratory examination indexes and progress within 28 d after hospitalization. Divided
the patients into death and survival groups, high RDWgroup and normal RDWgroup, and analyzed the differences of relevant indicators
between groups, and explored the relationship between RDW and recent prognosis of the patients.Results:The scores of acute
physiology admission and chronic health evaluation Ⅱ (APACHE Ⅱ ), and levels of calcitonin (PCT), allergic C-reactive protein
(hs-CRP), white blood cell count (WBC), neutrophil percentage (PMN) and blood sedimentation (ESR) were higher in death group than
in survival group (P < 0.05). The RDWlevel was also higher in death group than in survival group (P<0.05). Patients in high RDWgroup
had higher APACHE Ⅱ scores, higher levels of PCT, hs-CRP, WBC, PMN and ESR than those in normal RDWgroup, as well as higher
mortality (P < 0.05). Logistic regression analysis showed that RDW level was the independent risk factors for children with severe
pneumonia recent death (OR = 2.025, 95% CI: 1.252 ~ 4.243, P < 0.05). ROC curve analysis showed that the ROCAUC was 0.801 for
death of children with severe pneumonia, and the sensitivity was 82.0, specific degree was 74.4, the best cutoff point diagnosis was
16.35%.Conclusion:RDW levels may be independent risk factors for recently poor prognosis of children with severe pneumonia, and
may have a good predictive value for prognosis of children. |
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