| 郝军 吴海琴 刘之荣 王晓成 井泉 王玉梅.腔隙性和非腔隙脑梗塞患者的血压差异研究[J].,2016,16(22):4270-4273 |
| 腔隙性和非腔隙脑梗塞患者的血压差异研究 |
| Differences in Blood Pressure between Lacunar Infarction Patients andNon-lacunar Infarction Patients |
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| DOI： |
| 中文关键词: 腔隙性脑梗塞 血压 脑梗塞亚型 |
| 英文关键词: Lacunar infarction Blood pressure Cerebral infarction subtypes |
| 基金项目:陕西省教育厅专项科研计划项目（2012JK0828） |
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| 中文摘要: |
| 目的：比较腔隙性（LI）与非腔隙性（NLI）脑梗塞患者血压变化，评价血压与腔隙性脑梗塞的相关性。方法：选取在我院住院治
疗的249 例急性脑梗塞患者，根据不同亚型将患者分为腔隙性脑梗塞组（LI组，n=187）与非腔隙性脑梗塞组（NLI组，n=62），比较
两组患者血压差异，采用线性相关分析与cox 相关分析评估血压与脑梗塞及其危险因素的相关性。结果：LI组患者入院3 天收缩
压、舒张压显著高于NLI患者组，差异有统计学意义（分别P=0.003，P=0.009）；线性回归分析表明，入院时收缩压、入院第3 天收
缩压、入院第3 天舒张压与LI 显著相关（均P＜0.05）；cox 单因素与多因素分析表明，入院第3 天收缩压与LI 显著相关（分别
P=0.009 与P=0.006），与其他协变量不相关（均P＞0.05）。而患者出院时血压与mRS或NIHSS 不相关（分别P=0.788 和P=0.
898）。结论：与相同严重程度NLI患者比较，LI患者高血压与LI独立相关。LI患者血压显著高于NLI患者，二者差异虽与临床疾
病严重程度无关，但很可能是患者发生急性脑梗塞的根本原因。 |
| 英文摘要: |
| Objective:To compare the differences in blood pressure (BP) between lacunar infarction (LI) patients and Non-lacunar
Infarction (NLI) patients, and to evaluate the correlation between BP and LI.Methods:A total of 249 patients of acute cerebral infarction
were included. All patients were divided into lacunar infarction group (LI group, n=187) and non-lacunar infarction group (NLI group,
n=62) according to the different subtypes of lacunar infarction. Compared BP differences between the two groups of patients. Evaluated
the association between BP and infarction and risk factors by Linear correlation analysis and Cox correlation analysis.Results:Patients in
LI group had significantly higher systolic and diastolic BP than those in NLI patients group within 3 days admitted to hospital, and the
difference was statistically significant (respectively P=0.003, P=0.009). The linear regression analysis showed that systolic BP at
admission, systolic and diastolic BP at 3d after admission were significantly associated with LI (all P <0.05). The Cox univariate and
multivariate analysis showed that systolic BP at 3d after admission was significantly associated with LI (respectively, P=0.009 and P=0.
006), and other covariates were not correlated with LI (P>0.05). And the BP at discharge was irrelevant with NIHSS or mRS (respectively
P=0.788 and P=0.898).Conclusion:Compared the NLI patients of the same severity, hypertension in LI patients were independently
associated with LI. The BP of LI patients was significantly higher than that of the NLI patients. Although the difference was irrelevant
with the clinical severity of the disease, it may be the root cause of patients to have acute cerebral infarction. |
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