| Objective:To analysis the distribution and drug resistance of pathogenic bacteria in patients with stroke combined with
hospital acquired pneumonia, to provide laboratory reference for clincal retional selection of antibiotics.Methods:109 stroke patients
with hospital acquired pneumonia in our hospital fromMarch 2013 to September 2015 were investigated, and bacterial culture of morning
sputum or lower respiratory tract secretion collected by aseptic method were conducted, and the the drug resistance test of positive
pathogenic bacteria were carried out.Results:187 times of bacterial culture of morning sputum or lower respiratory tract secretion in 109
patients were launched, and 152 positive times (81.28%) including 283 strains of pathogenic bacteria, in which 192 strains of gram negative
bacilli (67.82%), 76 strains of grampositive bacilli (26.86%), and 15 strains of fungi (5.30%). Among the gram negative bacilli, the
drug resistance of , , , , to cefotaxime,
cefuroxime, mezlocillin, mezlocillin, cefuroxime and cefotaxime were the highest(66.18%, 65.31%, 70.97%, 64.00%, 71.43%respectively).
The drug resistance to chloramphenicol, piperacillin/tazobactam, chloramphenicol, cefepime, chloramphenicol were the lowest
(1.47%, 6.12%, 3.23%, 8.00%, 7.14%respectively). Among the the gram positive bacteria, the drug resistance of
, , to vancomycin, vancomycin, ampicillin were the highest (100.00%, 90.00%,
84.62%respectively). The drug resistance to erythromycin, erythromycin, erythromycin were the lowest (5.26%, 0.00%, 0.00%respectively).Conclusion:Gram negative bacilli is the main pathogenic bacteria in stroke patients with hospital acquired pneumonia in our hospital.
The pathogenic bacteria have a characteristics of high drug resistance and multiple drug resistance. It is should do that rational selection
of antibacterials to treatment in clinic. |
