| 余莉 武志远 洪婕 杨镒宇△ 左云龙 党润.儿童重症腺病毒肺炎的临床研究[J].,2016,16(19):3713-3716 |
| 儿童重症腺病毒肺炎的临床研究 |
| Clinical Characteristics of Severe Adenovirus Pneumonia in Children |
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| DOI： |
| 中文关键词: 重症肺炎 腺病毒 儿童 |
| 英文关键词: Severe pneumonia Adenovirus Children |
| 基金项目:广州市卫生局基金项目(2009-ZDi-15 ) |
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| 中文摘要: |
| 目的：分析儿童重症腺病毒肺炎(SAP)的临床特点。方法：选择2011 年01 月至2015 年01 月广州市妇女儿童医疗中心重症
监护室收治的被诊断为SAP 的患儿53 例。患儿入监护室后24 h内采集静脉血，检测血常规、血气、生化等指标，并结合病史与常
规生化等检测指标同步给出PCIS评分。根据患儿的转归，将所有患儿分为生存组和死亡组进行比较分析。结果：53 例重症腺病毒
肺炎患儿，男女比例为3.4:1，2 岁以下发病者48例，夏秋季发病共40 例。死亡组患儿共8 例(15.1％)，其LDH、AST、PaCO2水平、
肺叶受累数量、并发症种类较存活组患儿明显升高，危重症评分(PCIS)、血小板、白蛋白、PaO2水平、PaO2/FIO2比值均较生存组显
著降低(P均＜0.05)。结论：儿童SAP炎症反应重，常伴肺内外各种损害，早期的LDH、AST、白蛋白水平、血小板数量、PaO2、PaCO2、
PaO2/FiO2及PCIS 评分是疾病预后的早期预测指标，有助于临床医生对重症腺病毒肺炎患儿病情危重程度尽早作出正确判断。 |
| 英文摘要: |
| Objective:To analyze the clinical characteristics of severe adenovirus pneumonia (SAP) in pediatric patients.Methods:fifty three pediatric patients with SAP were reported. All data were collected from cases who were hospitalized in the Department of
PICU GuangZhou Women and Children Medical center from January 2011 to January 2015. Blood samples were taken within 24 hrs after
admission to ICU for blood routine test and other chemical routine test, pediatric critical illness score (PCIS) were also calculated. The
patients were divided into survival group (n=45) and death group (n=8) based on their hospital outcomes.Results:Among 53 patients,
47children were aged blow 2 years, with a male to female ratio of 3.4:1. The onset of 40 patients was in summer and autumn. 8 (15.1%)
patients died. levels of LDH, AST, PaCO2, number of the lung labors involved and number of complications in death group were more
than survival group, PCIS, number of platelet, levels of albumin, PaO2, PaO2/FIO2 were less than survival group, and the difference was
significant (P<0.05).Conclusion:SAP is a severe pneumonia with severe clinical manifestations with many complications. Levels of
LDH, AST, albumin, number of platelet, PCIS, PaCO2, PaO2, PaO2/FIO2 can predict the prognosis of critical illness patients. |
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