文章摘要
刘晓燕 张凌 卢怀美 曹进 刘珂琦.早期静脉营养支持对肺癌患者术后免疫功能的影响[J].,2016,16(17):3382-3384
早期静脉营养支持对肺癌患者术后免疫功能的影响
Influence of Early Venous Nutrition Support on Postoperative ImmuneFunction of Patients with Lung Cancer
  
DOI:
中文关键词: 肺癌  早期静脉营养支持  免疫功能
英文关键词: Lung cancer  Early venous nutrition support  Immune function
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作者单位
刘晓燕 张凌 卢怀美 曹进 刘珂琦 雅安市人民医院心胸外科雅安市人民医院护理部雅安市人民医院普外科重庆医科大学附属第二医院肿瘤科 
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中文摘要:
      目的:研究早期静脉营养支持对肺癌患者术后免疫功能的影响。方法:选取2013 年5 月到2015 年5 月我院收治的肺癌行 择期手术者110 例,按照随机数字表法将患者分为研究组和对照组,每组55 例,研究组术后第1 天给予早期静脉营养支持治疗, 对照组术后第2 天给予流质饮食,比较术前、术后第1 天和第7天T 细胞亚群、转铁蛋白(TFN)以及前白蛋白(PA)。结果:术后第 1 天两组CD3+、CD4+、CD8+均显著降低,与术前比较差异具有统计学意义(P< 0.05),研究组术后第7 天CD3+、CD4+、CD4+/CD8+ 显著升高,CD8+显著降低,与术前和对照组比较差异具有统计学意义(P< 0.05);研究组术后第7 天PA 和TFN 显著升高,与术前 和对照组比较差异有统计学意义(P<0.05)。结论:早期静脉营养支持能改善肺癌患者术后营养状况,提高其免疫功能。
英文摘要:
      Objective:To study the influence of early venous nutrition support on postoperative immune function of patients with lung cancer.Methods:A total of 110 patients with lung cancer, who were admitted to Ya'an People's Hospital from May 2013 to May 2015 and underwent operation, were randomly divided into study group(n=55) and control group(n=55). The study group was given early venous nutrition support 1 day after operation, while the control group was given liquid diet 2 days after operation, compared the T cell subsets, transferrin (TFN) and prealbumin (PA) before and 1 day and 7 days after operation.Results:CD3+, CD4+, CD8+ of two groups 1 day after operation were significantly cut down than before operation, the differences were statistically significant (P<0.05). CD3+, CD4+, CD4+/CD8+ of the study group 7 days after operation were significantly increased, CD8+ was significantly reduced than before operation and control group, the differences were statistically significant (P<0.05). PA and TFN of the study group 7 days after operation were significantly increased than before operation and control group, the differences were statistically significant (P<0.05).Conclusion:Early venous nutrition support can improve the postoperative nutritional status and immune function of patients with lung cancer.
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