| 任虹 张霖 范剑虹 黄凤 张琳.COOK双球囊导管在足月妊娠引产中的临床研究[J].,2016,16(17):3282-3285 |
| COOK双球囊导管在足月妊娠引产中的临床研究 |
| Clinical Study of COOK Double-balloon Catheter Application in LabourInduction for Full-termPregnancy |
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| DOI： |
| 中文关键词: COOK 双球囊导管 缩宫素 足月妊娠 宫颈成熟 引产 |
| 英文关键词: COOK double-balloon catheter Oxytocin Full-termpregnancy Cervical ripening Labour induction |
| 基金项目:上海市宝山区科学技术委员会自然基金项目（13-E-27） |
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| 中文摘要: |
| 目的：探讨宫颈双球囊导管在足月妊娠促宫颈成熟及引产中的有效性和安全性。方法：回顾性选择符合有引产指征、单胎头
位、宫颈评分<6 分的100 例足月妊娠孕妇进行分析，其中51 例采用COOK双球囊导管引产者为COOK组，49 例采用小剂量缩
宫素引产者为对照组，比较分析两组宫颈成熟度、引产效果、分娩方式、分娩结局、产后出血、新生儿窒息等情况。结果：100 例孕妇
引产指征主要是延期（过期）妊娠、羊水过少、妊娠期高血压、妊娠期糖尿病、妊娠合并甲减等。COOK组51 例促宫颈成熟有效49
例（96.08%），对照组有效16 例（32.65%），COOK 组促宫颈成熟有效率显著高于对照组，差异有统计学意义（P<0.05）。COOK 组诱
发临产时间明显少于对照组，两组差异有统计学意义（P<0.05）。COOK组阴道分娩41 例（80.39%），剖宫产10 例（19.61%）；对照
组阴道分娩20 例（40.82%），剖宫产29 例（59.18%），COOK组阴道分娩率明显高于对照组，剖宫产率明显低于对照组，两组差异
均有统计学意义（P<0.05）。两组之间的总产程、羊水污染率、新生儿窒息率、产后出血率等围产结局无显著差异（P>0.05）；COOK
组引产过程中出现不良反应6 例（11.76%），对照组5 例（10.20%），两组无显著差异（P>0.05）。结论：COOK双球囊导管促宫颈成
熟及引产效果明显优于缩宫素，且不增加不良反应的发生，由于操作简单，有效性和安全性高，值得国内临床推广。 |
| 英文摘要: |
| Objective:To investigate efficacy and safety of cervical double-balloon catheter in cervical ripening and full-term
labour induction.Methods:100 full-term pregnant women, who met indications for labour induction (single cephalic, cervical score<6),
were enrolled in a retrospective analysis. Among of them, 51 patients received labour induction with COOK double-balloon catheter
(COOK group), while 49 patients received labour induction with a small dose of oxytocin (control group). Cervical ripening, efficacy, delivery
mode, birth outcomes, and incidences of adverse reactions (postpartumhemorrhage, neonatal asphyxia, etc.) were compared.Results:The indications for labour induction of 100 pregnant women mainly included prolonged pregnancy, oligohydramnios, hypertension in
pregnancy, gestational diabetes mellitus, gestation hypothyroidism, etc. In the COOK group, the double-balloon catheter were effective in
51 cases (96.68%) on cervical ripening, while oxytocin could only promote cervical ripening in 16 cases (32.65%) in the control group,
the difference is statistically significant (P<0.05). The induced labour time of the COOK group was significantly less than that of the control
group (P<0.05). There were 41 cases of vaginal delivery (80.39%) and10 cases of cesarean section (19.61%) in the COOK group. In
the control group, the cases of vaginal delivery and cesarean section were 20 (40.82%) and 29 cases (59.18%), respectively. The percentage
of vaginal delivery in the COOK group was significantly higher than that in the control group. Maternal and neonatal adverse outcomes,
including duration, meconium rates, neonatal asphyxia, and postpartumhemorrhage rates were not significantly different between
two groups (P>0.05). During the courses of labour induction, adverse reactions occurred in 6 cases (11.76%) in the COOK group, and 5
cases in the control group (10.20%), the difference was not statistically significant (P>0.05).Conclusion:The efficacy of COOK double-
balloon catheter in promoting cervical ripening and full-term labour induction was better than oxytocin, and the catheter didn't increase
the risk of adverse reactions. Due to its simplicity in operation and high efficacy and safety, application of COOK double-balloon
catheter in domestic clinic is suggested. |
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