| 王凌峰 于长颖 王盛楠 由燕 周长华.氢吗啡酮术后镇痛对直肠癌Dixon 术后肠功能的影响[J].,2016,16(16):3146-3149 |
| 氢吗啡酮术后镇痛对直肠癌Dixon 术后肠功能的影响 |
| Effect of Postoperative Analgesic Hydromorphone on the Recoveryof Bowel Function after Dixon Operation |
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| DOI： |
| 中文关键词: 氢吗啡酮 直肠癌 Dixon术 术后镇痛 肠功能 |
| 英文关键词: Hydromorphone Rectal cancer Dixon Postoperative analgesic Bowel function |
| 基金项目:黑龙江省教育厅人文社会科学项目（12542153） |
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| 中文摘要: |
| 目的：探讨氢吗啡酮术后镇痛对直肠癌患者Dixon 术后肠功能恢复的影响。方法：选择直肠癌行Dixon 术的患者36例，随机
分为氢吗啡酮组（H组）和吗啡组（M组），每组18 人。两组患者均行静脉自控术后镇痛，其中H组镇痛药物采用氢吗啡酮+昂丹
司琼，而MS组则采用吗啡+昂丹司琼。术后常规医疗处理。结果：两组患者在年龄、性别、文化程度无统计学差异（P>0.05）。两组
患者术后VAS评分及HR、MAP变化均没有统计学差异（P>0.05）。与M组相比，H 组患者术后不良反应的发生率明显降低（P<0.
05），肠鸣音恢复时间、术后第一次排气时间和第一次排便时间均明显缩短（P<0.05）。结论：相对于吗啡，氢吗啡酮用于术后镇痛更
有利于直肠癌患者术后肠功能的恢复，并减少术后不良反应的发生率。 |
| 英文摘要: |
| Objective:To investigate the effect of postoperative analgesic hydromorphone on the recovery of bowel function in
patients after Dixon operation.Methods:36 rectal cancer patients that requiring Dixon operation were selected in this study. Patients were
randomly divided into Hydromorphone group (Group H) and Morphine group (Group M), 18 patients each group. Patients in Group H
were treated with hydromorphone and ondansetron for postoperative analgesia. While in Group M, patients were received morphine and
ondansetron as postoperative analgesic.Results:There were no difference in gender, age, educational level between two groups (P>0.05).
The HR, MAP and score of VAS were not different (P>0.05) between two groups. Compared with Group M, the complications incidence
rate after operation was significantly reduced in GroupH (P < 0.05). Shorten recovery time of bowel sounds, anal aerofluxus and
defecation was recorded in GroupH (P < 0.05).Conclusion:The hydromorphone can help reducing the incidence of negative reactions
and benefit bowel function recovery in patients with rectal cancer after Dixon operation. |
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