| 郭主声 梁思远 林偲思 朱学海 张丽.300 株鲍曼不动杆菌琼脂稀释法与纸片扩散法药敏检测结果比较[J].,2016,16(12):2281-2283 |
| 300 株鲍曼不动杆菌琼脂稀释法与纸片扩散法药敏检测结果比较 |
| Drug Sensitivity Test Results of 300 Strains of Acinetobacter Baumanniidetected by Agar Dilution Method and Disc Diffusion Method |
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| DOI： |
| 中文关键词: 鲍曼不动杆菌 药物敏感性试验 琼脂稀释法 纸片扩散法 |
| 英文关键词: Drug sensitivity test Agar dilution method Disc diffusion method |
| 基金项目:广东省东莞市科技计划医疗卫生类科研项目（20131051010236） |
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| 中文摘要: |
| 目的：比较琼脂稀释法和纸片扩散法对鲍曼不动杆菌的药敏试验结果。方法：随机挑选的300 株鲍曼不动杆菌,检测其标本
及科室的分布情况，并采用琼脂稀释法和纸片扩散法检测鲍曼不动杆菌对环丙沙星（CIP）、庆大霉素（CN）、阿米卡星（AK）、头孢
他啶（CAZ）、头孢吡肟（FEP）、左氧氟沙星（LEV）、氨苄西林- 舒巴坦（SAM）、妥布霉素（TOB）、美洛培南（MEN）、米诺环素（MH）、
头孢哌酮- 舒巴坦（SCF）11 种抗菌药物的敏感性，比较两种检测结果的差异。结果：300 株鲍曼不动杆菌主要分布在痰液标本中，
共214 株，占71.3%，主要来源于ICU 101 株（33.7%）及脑外科59 株（19.7%）。药敏检测结果显示，两种检测方法所得的SCF 和
MH 的敏感性差异具有统计学意义（P<0.05），其他9 种抗菌药物的药敏检测结果差异没有统计学意义（P>0.05）。结论：琼脂稀释
法和纸片扩散法对鲍曼不动杆菌药敏试验结果并不完全一致，临床用药时尤其要注意SCF 和MH 这两种药物药敏结果的可靠
性。 |
| 英文摘要: |
| Objective:To compare the drug sensitivity test results of 300 strains of Acinetobacter Acinetobacter baumannii detected by agar
dilution method and disc diffusion method.Methods:The distribution of specimens and departments of 300 strains of
,which were randomly selected, was detected. The sensitivity of Acinetobacter baumannii to ciprofloxacin (CIP), gentamicin
(CN), amikacin (AK), ceftazidime (CAZ), cefepime (FEP), levofloxacin (LEV), ampicillin sulbactam (SAM), tobramycin (TOB),
meropenem (MEN), minocycline (MH), cefoperazone-shubatan (SCF) was detected by agar dilution method and disc diffusion method
respectively. The difference of the test results was compared between the two methods.Results:300 strains of Acinetobacter baumannii
were mainly in the sputum specimens, totally 214 strains, accounting for 71.3%, which were mainly from the department of ICU 101
strains (33.7%) and cerebral surgery 59 strains (19.7%). Drug sensitivity test results showed that there were statistical significance in the
differences of susceptibility to SCF and MH detected by the two methods (P<0.05), but the differences of susceptibility of 9 antibacterials
had no statistical significance (P>0.05).Conclusion:The drug sensitivity test results for between agar dilution
method and disc diffusion method are not the same, we need to notice the reliability of susceptibility results for Acinetobacter baumannii MH and SCF should be
paid more attention to in clinical treatment. |
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