| 孙全贵 龙子 张晓迪 海春旭 王欣.抗氧化系统研究新进展[J].,2016,16(11):2197-2200 |
| 抗氧化系统研究新进展 |
| Novel Progress in Antioxidant System |
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| DOI： |
| 中文关键词: 抗氧化 氧化还原 活性氧 |
| 英文关键词: Antioxidant Redox Reactive oxygen species |
| 基金项目:国家自然科学基金青年基金项目（31400724）；陕西省自然科学基金项目青年基金项目（2014JQ4135） |
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| 中文摘要: |
| 氧化还原系统主要由活性氧、自由基、活性氧生成系统和抗氧化系统组成。大量的研究表明，氧化还原系统在机体多种生物
学功能中发挥关键的调节作用。抗氧化系统主要包括酶类抗氧化剂和非酶类抗氧化剂。抗氧化系统一方面可以通过调节活性氧
的水平影响各种生物学功能，另一方面各种酶类抗氧化剂和非酶类抗氧化剂本身也可以参与多种生化反应，调节机体功能。近年
来的研究表明，机体内除了典型的抗氧化酶，如超氧化物歧化酶和过氧化氢酶等，还存在多种抗氧化新型抗氧化酶，如硫氧还蛋
白、谷氧还蛋白和金属基质蛋白酶等。在本文中，我们将回顾近年来的一些文献，综述抗氧化系统的研究新进展，旨在为抗氧化系
统的深入研究提供理论基础。 |
| 英文摘要: |
| Redox system consists of reactive oxygen species (ROS), free radicals, ROS-generating system and antioxidant systems.
Large amount of evidence have shown that redox regulation play key roles in various biological processes. Antioxidant system
mainly includes enzymatic antioxidants and non-enzymatic antioxidants. On the one hand, antioxidant system can influence biological
processes through regulating ROS level; on the other hand, the antioxidant enzymes and non-enzymatic antioxidants participate in various
biological reactions, regulating a variety of functions. In the past few years, the studies have shown that in addition to classic antioxidant
enzymes, such as superoxide dismutase and catalase, some novel antioxidant enzymes like thioredoxins, glutaredoxins, and metallothionein
et al can also participate in the regulation of redox balance. In this review, the novel progress in antioxidant systems were summarized
to provide theoretical basis for further study of antioxidant system. |
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