| 刘德智 陈楠 范小勇 周霞 王慧娟 李莉.七氟烷与异丙酚联合瑞芬太尼对脊椎骨折麻醉效果的影响[J].,2016,16(9):1738-1741 |
| 七氟烷与异丙酚联合瑞芬太尼对脊椎骨折麻醉效果的影响 |
| Effect of Sevoflurane and Propofol Respectively Combined with RayleighFentanyl on SerumInflammatory Factors and Pain Index in Patients withSpinal Fracture |
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| DOI： |
| 中文关键词: 七氟烷 异丙酚 瑞芬太尼 脊椎骨折 疼痛指数 |
| 英文关键词: Sevoflurane Propofol Remifentanil Vertebral fracture Pain index |
| 基金项目:河南省科技攻关项目(092102300239) |
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| 中文摘要: |
| 目的：探讨七氟烷与异丙酚分别联合瑞芬太尼对脊椎骨折患者血清炎症因子及疼痛指数的影响。方法：选取2010年2 月至
2014 年12 月期间，我院收治的脊椎骨折患者124 例作为研究对象，按照麻醉方法随机分为两组：七氟烷组62 例，给予七氟烷联
合瑞芬太尼麻醉，异丙酚组62 例，采用异丙酚联合瑞芬太尼麻醉。观察比较两组患者临床麻醉效果，包括血清炎症因子变化、出
血量、疼痛指数及不良反应等情况并做出评价。结果：两组患者的出血量、血清炎症因子变化比较，差异无统计学意义（P > 0.05）。
两组镇痛效果均较佳，但异丙酚组的VAS评分优于七氟烷组，苏醒时间更短，差异有统计学意义(P < 0.05)。七氟烷组和异丙酚组
患者的总不良反应发生率分别为22.6 %和14.5 %，差异无统计学意义（P >0.05）。结论：七氟烷与异丙酚分别联合瑞芬太尼对脊椎
骨折患者的疼痛均具有较佳的镇痛效果，出血量低，不良反应少，安全性较高，临床应用价值较高。 |
| 英文摘要: |
| Objective:To investigate the effect of sevoflurane and propofol respectively combined with rayleigh fentanyl on serum
inflammatory factors and pain index in patients with spinal fracture.Methods:A total of 124 patients with vertebral fracture were divided
into two groups according to different methods of anesthesia, 62 cases in each group. The patients in sevoflurane group were treated with
sevoflurane combined with rayleigh fentany anesthesia and the patients in propofol group were given propofol combined with rayleigh
fentany anesthesia. The anesthesia effect was evaluated, including the change of serum inflammatory factors, the volume of blood loss,
the pain index and adverse reactions.Results:Compared with sevoflurane group, the seruminflammatory factors and the volume of blood
loss was no statistically significant（P>0.05）. The analgesic effect were excellent in two groups, but VAS scores in propofol group was
better than that of sevoflurane group, and the recovery time in propofol group was shorter with statistical significance (P<0.05). The total
incidence of adverse reactions in sevoflurane group and propofol group was 22.6%and 14.5%respectively, without statistical significance
between two groups (P>0.05).Conclusion:Sevoflurane and propofol respectively combined with rayleigh fentanyl have a great
analgesic effect for the patient with vertebral fractures, low blood loss, less adverse reaction and has high clinical value. |
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