Endothelial progenitor cells can proliferate, adhere, migrate and differentiate into vascular endothelial cells of the
original potential, and it can also repair endothelial injury and adult as a key link in angiogenesis. Endothelial progenitor cells is derived
from the bone marrow, at present in the bone marrow, peripheral blood, cord blood, now that can also be found in adipose tissue,
myocardial. Endothelial progenitor cells is similar to cell surface markers of stemcells, the function is also close to stem cells, but it does
not have the ability to self-renewal. In recent years, EPC has become a hot topic, the disease diagnosis, judging prognosis and target
therapy play an important role in coronary atherosclerosis disease, diabetes vascular disease, malignant tumor treatment of systemic or
local injections of EPC has broader prospects and application value. This article is for the basic situation, separati and culture techniques,
clinical application of endothelial progenitor cells. |