| 蔺建文 李淑敏 王苏平 曲竞 王虹.首发缺血性脑卒中患者血清Hcy和EPO水平的变化及临床意义[J].,2016,16(6):1104-1106 |
| 首发缺血性脑卒中患者血清Hcy和EPO水平的变化及临床意义 |
| Starting in Ischemic Stroke Patients' Serum Hcy and EPO Levels of Changeand Clinical Significance |
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| DOI： |
| 中文关键词: 首发缺血性脑卒中 血清Hcy EPO 变化 |
| 英文关键词: Starting of ischemic cerebral apoplexy SerumHcy EPO Change |
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| 中文摘要: |
| 目的：探究首发缺血性脑卒中患者血清同型半胱氨酸（Hcy）和红细胞生成素（EPO）水平的变化和意义。方法：于2013 年10
月-2015 年4 月我科收治的首发缺血性脑卒中患者中随机选取98 例作为观察组，另选取同期健康体检者98 例作为对照组，检测
患者的血小板、血浆纤维蛋白原（Fib）以及血白细胞水平，比较两组血清Hcy、EPO、血小板、Fib 及血白细胞水平，使用Logistic 回
归分析法评价缺血性脑卒中病发的危险因素，采用Spearman 法对血清Hcy 与EPO 间相关性进行分析。结果：观察组的Hcy
（23.52± 12.15）mIU/L 与EPO（34.61± 11.25）mIU/L水平显著高于对照组的（10.57± 2.18）mIU/L、（17.54± 5.83）mIU/L；观察组血
小板、血浆纤维蛋白原（fibrinogen，Fib）及血白细胞水平均高于对照组；差异均有统计学意义（均P＜ 0.05）。经Logistic 回归分析法
分析可知，Hcy为缺血性脑卒中病发的独立因素，经Spearman 相关性分析显示，首发缺血性脑卒中患者EPO 水平与Hcy呈正相
关。结论：缺血性脑卒中病发与血清Hcy和EPO 水平升高密切相关，且Hcy是导致缺血性脑卒中病发的高危因素。 |
| 英文摘要: |
| Objective:To explore the starting of ischemic cerebral apoplexy patients'serum Hcy and EPO level changes and
meaning.Methods:From October 2013 - April 2015 of 98 cases of starting in ischemic stroke patients were admitted in our department
were randomly selected as observation group. Selected the same period of health physical examination 98 cases was as control group,
detected the patients'platelets, plasma fibrinogen (Fib) and blood WBC level, compared two groups of serum Hcy, EPO, blood platelets,
Fib and WBC level, used Logistic regression analysis method to evaluate the risk factors of ischemic cerebral apoplexy disease, Spearman
method was used to analyze the correlation between serum Hcy and EPO.Results:The observation group's Hcy (23.52± 12.15) mIU/L
with EPO (34.61± 11.25) mIU/L were significantly higher than that of control group of (10.57± 2.18) mIU/L,(17.54± 5.83) mIU/L.
Observation group's blood platelet, Fib and white blood cell levels were higher than the control group; whcih were statistically significant
differences (all P<0.05). Analysis by Logistic regression analysis method, the results showed that the Hcy was the independent factors of
ischemic cerebral apoplexy disease. With Spearman correlation analysis showed that EPO starting in ischemic stroke patients with Hcy
levels were positively correlated.Conclusion:The ischemic cerebral apoplexy disease are closely associated with elevated serum Hcy and
EPO levels, and Hcy is lead to the risk factors of ischemic cerebral apoplexy disease. |
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