| 苟建军 张怡 王朝山 李力 蔡德泉.鼻内镜动力切削术对鼻前庭囊肿患者CRP、TNF-alpha、IL-6 及IL-8 的影响[J].,2015,15(25):4942-4945 |
| 鼻内镜动力切削术对鼻前庭囊肿患者CRP、TNF-alpha、IL-6 及IL-8 的影响 |
| Effect of CRP, TNF-alpha, IL-6 and IL-8 in Patients with Nasal Vestibular Cystby Nasal Endoscopic Surgery |
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| DOI： |
| 中文关键词: 鼻内镜 动力切削系统 鼻前庭囊肿 |
| 英文关键词: Nasal endoscopy Dynamic cutting system Nasal vestibular cyst |
| 基金项目: |
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| 中文摘要: |
| 目的：探讨鼻内镜下动力切削系统治疗对鼻前庭囊肿患者CRP、TNF-alpha、IL-6 和IL-8 的影响。方法：选取2012 年6 月至2013
年1 月我院收治的鼻前庭囊肿患者163 例，随机分为两组。实验组（80 例）行鼻内镜下动力切削系统行囊肿切除术，对照组（83
例）给予微波治疗。观察并比较两组患者手术前后血清CRP、TNF-alpha、IL-6 和IL-8 水平的变化情况，并比较两组患者手术情况、术
后并发症及远期疗效。结果：与对照组比较，实验组手术时间较长，术中出血量较多，差异具有统计学意义（P＜0.05），实验组术后
感染率较低，术后复发率较低；术后CRP、TNF-alpha、IL-6 和IL-8水平升高，与对照组相比，实验组各项指标较高（P<0.05）。结论：鼻内
镜下动力切削系统治疗鼻前庭囊肿具有较好的临床治疗效果，且复发率低，值得临床推广。 |
| 英文摘要: |
| Objective:To investigate the clinical efficacy of endoscopic dynamic cutting system for nasal vestibular cyst and its
effect on the level of CRP, TNF-alpha, IL-6 and IL-8.Methods:163 cases with nasal vestibular cyst that were treated in our hospital from
June 2012 to January 2013 were selected and randomly divided into two groups. 80 patients in the experimental group were given the
endoscopic dynamic cutting surgery for cyst resection, while another 83 patients in the control group were treated with microwave
therapy. Then the level of CRP, TNF-alpha, IL-6 and IL-8 of patients in the two groups were observed and compared before and after the
treatment, and the operative situations, the incidence of postoperative complications and the long-term effects of two groups were
compared.Results:The operation time and intraoperative bleeding of experiment group were more than the control group(P<0.05),
however, the postoperative infection rate and recurrence rate of experiment group was lower (P<0.05) compared with the control group.
The level of CRP, TNF-alpha, IL-6 and IL-8 was higher than before operation, and compared with the control group, the indexes in the
experimental group were higher (P<0.05).Conclusion:Endoscopic treatment of nasal vestibular cyst dynamic cutting systemhas a better
clinical therapeutic effect, worthy of clinical application. |
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