| 王竞 杨菁 贺艺 雷春荣 黄丽琼.慢性高血压合并妊娠发生子痫前期的危险因素分析[J].,2015,15(25):4888-4891 |
| 慢性高血压合并妊娠发生子痫前期的危险因素分析 |
| Analysis of the Risk Factors of Preeclampsia in Chronic Hypertensionwith Pregnancy |
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| DOI： |
| 中文关键词: 慢性高血压合并妊娠 子痫前期 危险因素 |
| 英文关键词: Chronic hypertension in pregnancy Preeclampsia Risk factors |
| 基金项目:国家自然科学基金项目(81070471) |
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| 中文摘要: |
| 目的：探讨慢性高血压合并妊娠发生子痫前期的危险因素，为筛查慢性高血压孕妇合并子痫前期提供参考依据。方法：选取
2009 年3 月~2013 年7 月我院收治的慢性高血压妊娠患者116 例，根据是否合并子痫前期分为慢性高血压合并妊娠组(NHDP
组)和慢性高血压合并子痫前期组(HDP 组)，比较两组患者不同孕期的血压、尿蛋白水平以及血液生化检测指标间的差异。结果：
两组间年龄、孕次、孕前尿蛋白水平、孕早期及孕中期的平均动脉压、尿蛋白水平间差异均无统计学意义(P>0.05)。HDP组孕前体
质指数、孕晚期的平均动脉压、尿蛋白水平、Hb、UA、LDH、FDP 均较NHPD组显著升高(P<0.05)，两组间Plt 水平差异无统计学意
义(P>0.05)。logistic 回归分析发现Hb、UA 及FDP 是慢性高血压妊娠患者并发子痫前期的危险因素。结论：凝血状况、血清尿酸水
平及肾功能变化是慢性高血压合并妊娠者发生子痫前期的危险因素。 |
| 英文摘要: |
| Objective:To investigate the risk factors of preeclampsia in chronic hypertension with pregnancy and provide the
references for screening pregnant women with chronic hypertension complicated with preeclampsia.Methods:116 cases with chronic
hypertension in pregnancy who were treated in our hospital from March 2009 to July 2013 were selected and divided into the chronic
hypertension in pregnancy group (NHDP group) and the chronic hypertension complicated with preclampsia group (HDP group)
according to the complicated with preeclampsia. Then the clinical data, blood pressure and urine protein during different periods of
pregnancy of the groups were observed and compared.Results:There was no significant difference between HDP group and NHDP
group in age, times of pregnancy and pre pregnancy urine protein content (P>0.05). The prepregnancy body mass index, average artery
pressure during the third trimester, urinary protein level, Hb, UA, LDH, FDP of HDP group were significantly higher than those of the
NHPD group(P<0.05). No significant difference was found in the Plt level between two groups(P>0.05); The logistic regression analysis
showed that Hb, UA and FDP were the risk factors of reeclampsia in chronic hypertension with pregnancy.Conclusion:The coagulation
status, serumuric acid level and change of renal function were risk factors of preeclampsia in chronic hypertension with pregnancy. |
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