| 李梁蜜 方芳 曹文英 李承 冯裕星.阿尔茨海默病和血管性痴呆与血糖代谢水平的关系及危险因素分析[J].,2015,15(15):2932-2934 |
| 阿尔茨海默病和血管性痴呆与血糖代谢水平的关系及危险因素分析 |
| Relationship between Alzheimer's Disease, Vascular Dementia and GlucoseMetabolismand Their Risk Factors |
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| DOI： |
| 中文关键词: 阿尔茨海默病 血管性痴呆 血糖 危险因素 |
| 英文关键词: Alzheimer's disease Vascular dementia Blood glucose Risk factors |
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| 中文摘要: |
| 目的：研究阿尔茨海默病和血管性痴呆与血糖代谢水平的关系及危险因素。方法：选取2013 年12 月到2014 年12 月我院
收治的阿尔茨海默病80 例（A 组）和血管性痴呆70 例（B 组），另选取同时期无痴呆者70 例（对照组），测量三组入选者血糖各指
标水平，并分析阿尔茨海默病和血管性痴呆的危险因素。结果：A 组和B 组空腹血糖（FPG）均显著高于对照组，胰岛素降解酶
（IDE）显著低于对照组，比较差异具有统计学意义（P＜0.05）；B 组糖尿病、冠心病和高血压疾病的发病率显著高于A 组和对照
组，比较差异具有统计学意义（P＜0.05），A组和B组高血脂发病率均显著高于对照组，比较差异具有统计学意义（P＜0.05）。结
论：阿尔茨海默病和血管性痴呆均与FPD、IDE以及高血脂有较大关系，高血压、冠心病和糖尿病与血管性痴呆有较大关系。 |
| 英文摘要: |
| Objective:To study the relationship between alzheimer's disease, vascular dementia and glucose metabolism and their
risk factors.Methods:Selected 80 cases of patients with alzheimer's disease (as A group), 70 cases of patients with vascular dementia(as
group B) and another 70 people without dementia (as control group) who were treated in our hospital fromDecember 2013 to December
2014, detected the different index levels of blood glucose in three groups, and analyzed the risk factors for Alzheimer's disease and vascular
dementia.Results:Fasting plasma glucose (FPG) of A group and B group were significantly higher than the control group, while the
insulin-degrading enzyme (IDE) was significantly lower than the control group,the differences were statistically significant(P<0.05); The
incidence of diabetes, coronary heart disease and hypertension of B group were significantly higher than A group and control group, the
differenceswere statisticallysignificant (P<0.05), and the incidence of high cholesterol ofAgroup andBgroupwere significantlyhigher than
control group, the differences were statistically significant (P<0.05).Conclusion:FPG, IDE and high cholesterol are greatly related to
Alzheimer's disease and vascular dementia, and hypertension, coronary heart disease and diabetes are greatly related to vascular dementia. |
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