| Primary Biliary Cirrhosis (PBC), a kind of autoimmune liver disease, is characterized by its serum antibody and
chronic, non-suppurative devastating cholangitis. Ursodesoxycholic acid (UDCA), as the first-line therapy drug for the treatment of PBC,
can make the biochemical indicators and survival time of patients with PBC get significantly improved. Though the treatment of PBC is
still a tough problem on clinic and there are still 40% of patients with PBC responsing poorly to Ursodesoxycholic acid treatment, liver
transplantation is the only effective treatment for patients with final-stage PBC. In this paper, we simply summarize the latest progress of
drug treatment of PBC, including Ursodesoxycholic acid, budesonide, immunosuppressants, Bert, 6alpha-ethyl chenodeoxycholic acid,
rituxan and antiretroviral drugs and so on, hoping that this article will be useful for the treatment of PBC. |
