| 田龙元 杨华丽 王群伟.胰腺癌相关肿瘤标志物研究进展[J].,2015,15(13):2588-2591 |
| 胰腺癌相关肿瘤标志物研究进展 |
| The Research Advances of Tumor Markers on Pancreatic Cancer |
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| DOI： |
| 中文关键词: 胰腺癌 早期诊断 血清标志物 基因标志物 表观遗传学标志物 |
| 英文关键词: Pancreatic Cancer Early diagnosis Serummarkers Genetic markers Epigenetic markers |
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| 中文摘要: |
| 胰腺癌起病隐匿，进展快，预后差，发病率约等于死亡率。胰腺癌死亡率高的原因有发病机制不明，缺乏有效的早期诊断和
预后的肿瘤标志物，进展期相关治疗效果不理想。近年来在血清标志物、基因标志物、表观遗传学标志物等分子生物技术及生物
信息学方面的发展为胰腺癌的诊断，尤其是早期诊断、评估预后和监测早期复发提供了新的途径。本文就近期胰腺癌相关肿瘤标
志物的研究进展作一综述。 |
| 英文摘要: |
| The pancreatic cancer has a concealed onset, rapidly advancing, poorly prognosis and nearly the incidence coincide
mortality. The reasons of the high mortality rate of pancreatic cancer are the unknown mechanisms, lacking of early diagnostic and prognostic
tumor markers and once developed suggests a poor treatment effect. Currently, with the development of molecular biotechnology
and bioinformatics, such as serum markers, genetic markers and epigenetic markers, we could have a shortcut in early diagnosis, assessment
of prognosis and monitoring early recurrence in pancreatic cancer. Here, we review the current progress on related tumor markers of
pancreatic cancer. |
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