| 臧凤莉 白 宁 王宝菊 李婷婷 史立军.贲门失弛缓症治疗的现状和进展[J].,2015,15(6):1160-1164 |
| 贲门失弛缓症治疗的现状和进展 |
| The Development and Progress of Cardia Achalasia Treatment |
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| DOI： |
| 中文关键词: 贲门 失弛缓症 下食管括约肌 肉 毒毒素注射 气囊扩张术 肌切开术 |
| 英文关键词: Achalasia Lower Esophageal Sphincter BT injection Pneumatic Dilation Myotomy |
| 基金项目:黑龙江省科技公关课题（ WB07C04） |
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| 中文摘要: |
| 贲门 失弛缓症尚无根治的方法，但 90 %以上的患者经积极治疗后可得到缓解。对于初发贲门 失弛缓症患者， 临床症状轻， 可
通过调整饮食习 惯及药物治疗缓解症状， 随着时间的延长， 病情逐渐加重， 药物治疗 不满意时， 可行内 镜下治疗。 内 镜下球囊扩张
治疗、 BT 注射治疗及暂时性支架置入治疗， 均具有良好的短期疗 效和安全性， 但长期疗 效暂时性支架置入治疗 优于扩张治疗 ， 扩
张治疗优于 BT 注射治疗 。对老年患者、不能行扩张或手术者，可予内 镜下 BT 注射治疗。 POEM 作为一种新技术， 具有较好的发
展前景。 手术治疗创伤大， 费用 高， 但是对于扩张治疗失败或需多 次扩张治疗的患者， 手术治疗 是一种有效的治疗方式。 本文就贲
门 失弛缓症的治疗现状及进展作此综述，旨 在为患者寻找一种个性化、有效、创伤小、费用 低的治疗方式。 |
| 英文摘要: |
| Although there was no radical cure for patients with achalasia at present, more than 90% of patients can be alleviated
after active treatment. For primary achalasia patients with moderate clinical symptoms, adjusting the diet and drug therapy can relieve
their symptoms.Gradually over time, the condition worsened, the medication unsatisfied,endoscopic therapy is feasible. Pneumatic
dilation、 botulinum toxin (BT) injection and temporary stenting treatment under endoscope have good short-term efficacy and safety, But
the long-term curative effect of temporary stenting treatment is better than that of dilation， while dilation therapy is superior to the BT
injection therapy. For those elderly and not suitable for dilation or surgery patients, BT injection therapy under endoscope is feasible.
POEM, as a kind of new technology, has good prospects for development. Although Surgical treatment has serious trauma and high cost,
it is an effective treatment for those patients whose dilation treatment fail or those who need multiple dilation treatment .This paper
reviewed current status and advance about the treatment of achalasia, aimed at looking for a personalized, effective, minimally invasive
and low-cost treatment for patients. |
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