| 边瓯 任奕 何瑞 马宁 丁亮.大剂量甲泼尼龙救治结缔组织病合并急性呼吸窘迫综合症及文献复习[J].,2015,15(4):682-684 |
| 大剂量甲泼尼龙救治结缔组织病合并急性呼吸窘迫综合症及文献复习 |
| High Doses of Methylprednisolone Treatment for an Patient with ConnectiveTissue Disease Accompanied by Acute RespiratoryDistress Syndrome-a Case Report |
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| DOI： |
| 中文关键词: 高龄 呼吸窘迫综合症 糖皮质激素 |
| 英文关键词: Elderly Respiratory distress syndrome Glucocorticoids |
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| 中文摘要: |
| 目的：探讨糖皮质激素在急性呼吸窘迫综合症（ARDS）治疗中的意义及进展。方法：回顾性分析我科采用大剂量甲泼尼龙救
治的1 例结缔组织病合并ARDS高龄患者诊治过程，并结合文献进行复习。结果：患者采用大剂量甲泼尼龙治疗后，有效改善肺
部功能，减轻肺纤维化。随访至今病情稳定。结论：在ARDS治疗过程中，激素发挥重要作用，激素剂量及疗程的应用需因病而异。
关键词：高龄；呼吸窘迫综合症；糖皮质激素 |
| 英文摘要: |
| Objective:To evaluate the role of glucocorticoids in prevention and treatment of acute respiratory distress syndrome
(ARDS).Methods:The clinical data of one case of the elderly patient with connective tissue disease accompanied by ARDS was analyzed
retrospectively and reported, then relevant literature was reviewed.Results:After the elderly patient underwent high doses of
methylprednisolone treatment for a short period early in the course of ARDS, the lung function was improved immediately and progression
to fibroblast proliferation and collagen deposition was prevented. The patient was followed up with good prognosis in time of half a
year post-treatment.Conclusion:Glucocorticoid therapy is benefit in the course of ARDS, and the dosage and duration should be accepted
according to its causes. |
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