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目的：应用实时三平面(real-time tri-plane)定量组织速度成像技术(quantitative tissue velocity imaging,QTVI)分析正常人不同年龄左心房局部心肌舒缩功能特点，并探讨正常值区间。方法：选取202 例健康志愿者，按年龄分为青年组A 组≤ 44岁(63 例)，中年组B 组45～59 岁（87 例），老年组C组≥ 60 岁（52 例），应用实时三平面组织多普勒成像(tissue Doppler imaging, TDI)软件中的 QTVI技术，同步测量左心房基底段六个壁(房间隔、外侧壁、前壁、下壁、前间隔、后壁)收缩期心肌组织运动速度(Vs)、舒张早期心肌组织运动速度(Ve)、舒张晚期心肌组织运动速度(Va)的测量值，并计算出各壁不同时相的测量值95 %可信区间，分析不同年龄组各房壁在各时相心肌运动速度特点。结果：各年龄组不同房壁在相同时相的心肌运动速度测量值比较差异无统计学意义(P 均 >0.05)；同一房壁Vs、Ve 值在A 组、B 组与C 组差异无统计学意义(P>0.05)，Va 值在A 组与B组差异无统计学意义(P>0.05)，Va 在A组与C组、B组与C 组差异有统计学意义(P<0.05)。将A组与B组整合D组后，D组与C组左心房六个壁（房间隔、外侧壁、前壁、下壁、前间隔、后壁）心肌组织运动速度（Vs、Ve、Va）的95 %可信区间分别为：D 组(4.73～5.17、-7.49～-5.83、-5.57～-4.62) cm/s、(5.93～6.82、-8.75～-6.93、-6.31～-5.26)cm/s、(5.31～6.22、-7.89～-6.23、-6.03～-4.91)cm/s、(4.24～5.18、-6.98～-5.42、-6.01～ -4.87)cm/s、(4.94～5.13、-7.23～-6.11、-5.76～-4.71)cm/s、(5.15～6.17、-7.15～-5.44、-6.05～-4.88)cm/s；C 组（4.83～5.48、-7.23～-5. 95、-5.63～-4.67）cm/s、（5.97～6.99、-8.70～-7.03cm/s、-6.36～-5.28）cm/s、（5.53～6.31、-7.99～-6.29、-6.09～-4.99）cm/s、（4.86～ 5.21、-6.94～-5.48、-6.04～-4.91）cm/s、（5.53～6.31、-7.99～-6.29、-6.09～-4.99）cm/s、（5.23～6.25、-7.08～-5.47、-6.08～-4.90）cm/s。结论：实时三平面QTVI技术在定量评价正常人左房机械功能方面具有一定可行性。

英文摘要:

Objective:To analyze left atrial normal myocardial diastolic function by real-time three plane (real-time tri-plane) quantitative tissue velocity imaging(QTVI), and investigate normal value range in the different ages.Methods:202 healthy volunteers are divided into three groups:A group:≤ 44-year-old (63 cases), B group:45～59-year-old（87 cases）, and C group:≥ 60-year-old（52 cases）. Synchronous measurement of myocardial tissue motion contraction period velocity(Vs), early diastolic myocardial velocity (Ve), late diastolic myocardial tissue motion velocity (Va) of the left atrial basal segment six walls (atrial septum, lateral wall, anterior wall, inferior wall, anterior septum, posterior wall by real-time tri-plane of tissue Doppler imaging (TDI) and QTVI in software technology, and calculating values of 95% confidence interval of walls at different phases, analyzing characteristics of velocity of myocardial motion in the different walls at the same phase.Results:The measurements of left atrial myocardial motion velocity of different walls during the same phase in different age groups had no significant difference (P>0.05). The measurements of left atrial myocardial motion velocity of different walls during Vs, Ve phase in A, B and C groups had no significant difference (P>0.05), the measurements of left atrial myocardial motion velocity of the same walls during Va phase in A and B groups had no significant difference (P>0.05), and the difference was evident in A and C groups B and C groups (P＜0.05). By the A group and B group integration for D group, the 95 % confidence interval in D and C groups during systolic, early diastolic, and late diastolic periods, lateral wall, anterior wall, inferior wall, anterior septum, posterior wall of left atrium myocardial tissue motion velocity were: D group (4.73～5.17, -7.49～-5.83, -5.57～-4.62) cm/s, (5.93～6.82, -8.75～-6.93, -6.31～-5.26)cm/s, (5.31～6.22, -7.89～-6.23, -6.03～-4.91)cm/s, (4.24～5.18, -6.98～-5.42, -6.01～-4.87)cm/s, (4.94～5.13, -7.23～-6.11, -5.76～-4.71)cm/s, (5.15～6.17, -7.15～-5.44, -6.05～-4.88)cm/s; C group（4.83～5.48, -7.23～ -5.95, -5.63～-4.67）cm/s,（5.97～6.99, -8.70～-7.03, -6.36～-5.28）cm/s,（5.53～6.31, -7.99～-6.29、-6.09～-4.99）cm/s,（4.86～5.21, -6.94～-5.48, -6.04～-4.91）cm/s, （5.53～6.31, -7.99～-6.29, -6.09～-4.99）cm/s, （5.23～6.25, -7.08～-5.47, -6.08～-4.90）cm/s.Conclusion:Real-time tri-plane QTVI technology has potential role in evaluating left atrial mechanical function of normal people quantitatively.

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