| 唐庆业 刘文举 蒲宏伟 李文霞 刘正金.阿托伐他汀钙片治疗急性冠脉综合征的临床疗效[J].,2015,15(3):507-509 |
| 阿托伐他汀钙片治疗急性冠脉综合征的临床疗效 |
| Clinical Curative Effect of Atorvastatin in the Treatment of Patients withAcute Coronary Syndrome |
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| DOI： |
| 中文关键词: 阿托伐他汀 急性冠脉综合征 疗效 |
| 英文关键词: Atorvastatin Acute coronary syndrome Effect |
| 基金项目: |
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| 中文摘要: |
| 目的：探讨阿托伐他片汀治疗急性冠脉综合征（ACS）的临床疗效。方法：选择2013 年3 月至2013 年12 月我院收治的156
例ACS 患者，按随机字数表法分为实验组和对照组各78 例，两组均采取常规治疗，实验组在此基础上加用阿托伐他汀钙片，对照
组则用辛伐他汀滴丸。对比两组治疗效果及心血管事件发生率。结果：两组治疗后总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆
固醇( LDL-C)、血清高敏C 反应蛋白(hs-CRP)、纤维蛋白原(Fg)和尿酸水平均明显下降，且实验组下降更明显，比较差异均有统计
学意义（P＜0.05）；治疗期间实验组心血管事件发生率率为8.97%（7/78），显著低于对照组的24.36%（19/78），比较差异均有统计
学意义（P＜0.05）。结论：阿托伐他汀片治疗ACS 的临床效果优于辛伐他汀滴丸，能有效降低心血管事件的发生，值得的临床推
广。 |
| 英文摘要: |
| Objective:To investigate the effect of atorvastatin in the treatment of patients with acute coronary syndrome.Methods:156 cases of patients with acute coronary syndrome in our hospital from March 2013 to December 2013 were randomly divided into
experimental group and control group, each group with 78 cases. The two groups were taken routine treatment, the control group was
added with simvastatin, while the experimental group was given atorvastatin in addition. The therapeutic effect and the incidence rate of
cardiovascular events of the two groups were compared.Results:The levels of total cholesterol (TC), triglyceride (TG), low-density
lipoprotein cholesterol (LDL-C), serum high-sensitivity c-reactive protein (hs-CRP), fibrinogen (Fg) and uric acid of the two groups
significantly decreased after treatment, and the experimental group decreased more obviously (P<0.05); The incidence rate of
cardiovascular events of the experimental group was 8.97% (7/78), significantly lower than 24.36% (19/78) of control group during the
treatment period (P<0.05).Conclusion:Atorvastatin in the treatment of patients with acute coronary syndrome has a significant effect
compared simvastatin, and can effectively reduce the incidence of cardiovascular events, which is worthy of further clinical application. |
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