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目的：探讨糖尿病性黄斑水肿的三维光学相干断层扫描技术(3D-OCT)与多焦视网膜电图(mERG)检查结果的相关性。方法：随机选择糖尿病性黄斑水肿患者40 人60 只眼，经荧光造影检查示黄斑部有持续性的荧光渗漏、囊样水肿，3D-OCT 示黄斑中心凹厚度大于170um，对黄斑中心凹旁上、下、鼻、颞约750um 处视网膜神经上皮层处厚度进行OCT 自带软件的分析测量。随机选择18 人35 只年龄相配的正常眼为对照组以同样方法行3D-OCT 黄斑旁四个方位的神经上皮厚度测量。两组用同种方法行常规黄斑部mERG 检查。所有数据应用SPSS13.0 统计软件进行处理，分析3D-OCT 与mERG 在影像学方面的相关性。结果：两组被检查者检查结果经统计学处理后对比发现：被检查者黄斑中央5° 、10° 区域N1、P1 波反应密度绝对值与黄斑中心凹神经上皮层厚度具有显著的相关性(P<0.05)。结论：糖尿病性黄斑水肿的神经上皮厚度的改变与黄斑区mERG的改变具有显著相关性，主要表现为黄斑中央5° 和10° 区域mERG 各波反应密度的改变，且有神经上皮厚度增加的越大，mERG各波反应密度的降低的幅度也随之变大的趋势。

英文摘要:

Objective:To determine the correlation between 3D-OCT and mERG of the eye with diabetic macular edema.Methods:3D-OCT and mERG were performed on 60 eyes of 40 cases of diabetic macular edema by random selection. Macular fluorescence imaging with fluorescence leakage, OCT foveal thickness is more than checking 170 滋m. Checking fovea by software of 3D-OCT, adjacent to the fovea, inferior, nasal, temporal, about 750um at the retinal at the measurement. 35 eyes of 18 people aged-matched were randomly selected as normal eye control group, in the same way, macular four azimuth neuroepithelial thickness measurement checked by 3D-OCT. Macular mERG checked during the two groups of patients with the same routine. The data were processed with software SPSS13.0. The two groups of patients were compared with two groups of data link, so as to analyze the 3D-OCT and mERG correlation in terms of imaging.Results:We found that, after statistically treated, there was significant correlation among macular central 5 ° and 10 ° area N1, P1 ,the absolute value of response densities and the fovea epithelial thickness (P<0.05).Conclusion:The diabetic macular edema in epithelial thickness changes in a certain area mERG related, mainly for the central macular region 5° and 10° mERG lower density of the wave reflection, amplitude and neuroepithelial thickness change, the greater the mERG reduces the amplitude of each wave response density.

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