| Objective:To explore the effects of enteral nutrition on inflammation factors and immune function in critically ill
patients with long-term fasting.Methods:56 critically ill patients who were treated in our hospital and had fasted for 1 4 days or more
were selected, the levels of endotoxin, tumor necrosis factor-琢, C reactive protein,white blood cells, interleukin, T lymphocyte subsets
and histocompatibility antigens resistance-DR in peripheral blood were measured before enteral nutrition and on 1 , 3, 7 days after enteral
nutrition, and the indexes were compared before and after enteral nutrition.Results:The levels of endotoxin, tumor necrosis factor-琢, C
reactive protein, white blood cells, interleukin-1 and interleukin-6 after 1, 3 days of enteral nutrition were higher than before enteral
nutrition, and the difference was statistically significant (P<0.05); The levels of CD4, CD4/CD8 after 7 days of enteral nutrition was
higher than before enteral nutrition, the differences were statistically significantly (P<0.05); There was no statistical difference in enteral
nutrition, tumor necrosis factor-琢, C reactive protein,interleukin-1 , interleukin-6, interleukin-4, interleukin-10,CD3 or histocompatibility
antigens resistance-DR (P>0.05).Conclusion:Systemic inflammatory responses in critically ill patients with long-term fasting was
significant after enteral feeding, but can alleviate with the continue period of enteral feeding and can modify the immune function of
patients． |
