| 栗村瑞 王玉洁 王运灵 王冬婷 杨天德.静注氟比洛芬酯预防肺叶手术中全麻患者苏醒期躁动的临床研究[J].,2014,14(35):6870-6873 |
| 静注氟比洛芬酯预防肺叶手术中全麻患者苏醒期躁动的临床研究 |
| The Clinical Research of Intravenous Injection of Flurbiprofen Ester on thePrevention of Emergence Agitation after General Anesthesia in Lung Surgery |
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| 中文关键词: 氟比洛芬酯 躁动 疼痛评分 肺叶手术 |
| 英文关键词: Flurbiprofen ester Agitation Visual analogue scale Lung surgery |
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| 中文摘要: |
| 目的： 探讨肺叶手术中超前应用 氟比洛芬酯对减轻全身麻醉苏醒期躁动发生率的影响。 方法： 60 例 肺叶切除术患者随机分
为 A 组和 B 组， 每组 30 例，两组均常规诱导全麻气管插管， 术中瑞芬、丙泊酚、维库溴铵泵住维持麻醉， A 组于术前给予氟比洛芬
酯 1 MG/KG。 比较两组躁动得分、苏醒后 (1 0 min、 30 min、1 h、2 h、 4 h、 24 h)六个时间点疼痛评分及不良反应发生率。 结果： 两组出
血时间、拔管时间、麻醉时间 差异均无统计学意义（均 P>0.05）； A 组患者的躁动得分显著低于 B 组， 差异有统计学意义（ P<0.05）；
两组的 VAS 评分差异有统计学意义（ P<0.05）， 不同 时间 点的 VAS 评分差异有统计学意义（ P<0.05）， 分组与时间 之间 存在交互作
用（ P<0.05）； A 组患者的不良反应发生率低于 B 组， 差异有统计学意义（ P<0.05）。 结论： 肺叶手术中超前应用 氟比洛芬酯具有良好
的镇痛效果， 可以降低全身麻醉苏醒期躁动的发生率。 |
| 英文摘要: |
| Objective:To expore the effect of flurbiprofen ester preemptively used in lung surgery on reducing the incidence of
emergence agitation after general anesthesia.Methods:60 lobectomy patients were randomly divided into two groups with 30 cases in
each group. General anesthesia and tracheal intubation were inducted commonly to all patients in the two goups: remifentanil, propofol
and vecuronium bromide were pumped to make anesthesia maintain. In addition, 1 MG/KG flurbiprofen ester was given to group A
before the lung surgery. Agitation score, visual analogue scale after revival (1 0 min, 30 min, 1 h, 2 h, 4 h, 24 h) and incidence of adverse
reactions were compared between two groups.Results:The bleeding duration, extubation time and anesthesia time between two groups
showed no significant statistical differences(P>0.05), while the agitation score of group A was lower than that of group B(P<0.05), visual
analogue scale between two groups presented significant statistical differences(P<0.05), visual analogue scale at different time points had
significant statistical differences(P<0.05), there was interaction between groups and time(P<0.05); The incidence of adverse reactions of
group A was lower than that of group B (P<0.05).Conclusion:Application of flurbiprofen ester before lung surgery has good effect of
analgesia, and it can reduce the incidence of emergence agitation after general anesthesia. |
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