| Objective:To observe the effects of dezocine combined with propofol intravenous anesthesia in painless gastrointestinal
endoscopy.Methods:100 cases of patients undergoing painless gastrointestinal endoscopy were randomly divided into the
observation group and the control group with 50 cases in each group, the observation group received dezocine combined with propofol
anesthesia while the control group were given fentanyl and propofol intravenous anesthesia, onset time of anesthesia, consciousness loss
time, postoperative goggle time, dosage of propofol and respiratory, and hemodynamic changes were compared between two groups of
patients.Results:①The open time and the dosage of propofol of the observation group was significantly lower than those of the control
group, and the difference was statistically significant (t1=9.37, t2=69.72, P＜0.05); ②The RR, SpO2 of the control group before anesthesia,
at 1 min after intubation, during operation and 30min post operation had statistical significant difference(F1=15.241, F2=11.383, P＞0.05),
the two indicators at 1min after intubation and during operation decreased, MAP and HR showed no significant differences among
different time points (F1=15.241, F2=11.383, P＞0.050). The MAP, HR, RR, SpO2 in the observation group presented no significant
difference among different time points (F1=9.34, F2=12.35, F3=5.34, F4=12.83, P＞0.05), the patients in observation group had more stable
respiration and oxygen saturation. ③ The incidence rate of adverse reaction in observation group was 4%, significantly lower than in the
control group (12%), and the difference was statistically significant (x2=8.452, P＜0.05).Conclusion:Dezocine propofol anesthesia has
good analgesic effect in painless gastrointestinal endoscopy with high safety and it is worth promotion in application. |
