| 李宝丰 陈蓓 李梅 章莹 赵涛 李静 任东青 郭国祯.电磁脉冲对清醒大鼠尾动脉血压的影响[J].,2014,14(32):6201-6204 |
| 电磁脉冲对清醒大鼠尾动脉血压的影响 |
| Effects of Electromagnetic Pulses on Caudal Arterial Blood Pressureof Conscious Rats |
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| DOI： |
| 中文关键词: 电磁脉冲 动脉血压 心率 大鼠 |
| 英文关键词: Electromagnetic pulse (EMP) Arterial blood pressure Heart rate Rats |
| 基金项目:国家自然科学青年基金项目（81000819） |
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| 中文摘要: |
| 目的：观察电磁脉冲(electromagnetic pulses, EMP) 对清醒大鼠动脉血压和心率的影响。方法：适应性血压测量1 周后的14
只健康成年雄性SD大鼠按体重随机分为假辐照组和辐照组，每组7 只，在锥形平板GTEM 小室内接受EMP辐照，EMP辐照参
数为：场强200 kV/m，脉冲前沿3.5 ns，脉宽14 ns，重复频率1 Hz，辐照后用无创性尾套式血压测量仪测量2 hr 至1 wk 内大鼠动
脉血压和心率变化规律。结果：照后3 d大鼠动脉血压（收缩压、舒张压和平均动脉压）与假辐照组相比下降显著（P＜0.05），12 h
有下降趋势，其他时间未见显著性差异（P＞0.05）；辐照对大鼠心率也无明显影响（P＞0.05）。结论：EMP辐照可以引起大鼠血压
一过性降低；对大鼠心率无明显影响。 |
| 英文摘要: |
| Objective:To investigate the effects of electromagnetic pulses (EMP) on arterial blood pressure and heart rate of conscious
rats.Methods:14 male Sprague-Dawley rats, the blood pressure of which have been measured for a week, were randomly divided
into two groups with 7 rats for each group. They were subjected to sham exposure or 200 kV/m [200 kV/m, 3.5 ns duration, 14 ns width,
1Hz and 200 pulses] EMP fields in a tapered parallel plate GTEMcell. The arterial blood pressures and heart rates were evaluated from 2
hours to 1 week after exposures by a noninvasive tail-cuff photoelectric sensor sphygmomanometer.Results:3d after the EMP irradiation,
arterial blood pressures [systolic, mean and diastolic pressures] decreased significantly(P＜0.05). There was a tendency to decrease
at the 12th hour after exposures. There was no significant differences at other times（P＞0.05）. There was no change in heart rates by the
exposures（P＞0.05）Conclusion:EMP irradiation can decrease the arterial blood pressures of conscious rats in a short period of time.
No influence of EMP was detected on the heart rate. |
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