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目的：探讨前列腺增生伴II型糖尿病患者的尿流动力学改变,并对该类患者提出合理的治疗和处理。方法：选取从2010 年9 月～2013 年9 月在本院泌尿外科一病房行经尿道前列腺电切，术后病理诊断为前列腺增生术前行尿流动力学检查的患者349 例，分为单纯前列腺增生组158 例(对照组)及前列腺增生合并II型糖尿病组191 例(研究组)，前列腺增生合并II型糖尿病组又分为两个亚组，即空腹血糖≤ 6.1 mmol/L组（亚1 组）96 例及空腹血糖>6.1 mmol/L组95 例（亚2 组）。比较各组患者尿流动力学各项检查结果。结果：1)、比较亚2 组和对照组患者残余尿量、最大尿流率、最大尿流率时逼尿肌压、最大逼尿肌压及顺应性，P 值均 <0.05。2)、亚1 组和对照组患者残余尿量、最大尿流率、最大尿流率时逼尿肌压、最大逼尿肌压及顺应性，除亚1 组病程<5 年的残余尿量、顺应性P 值>0.05 外，其他均<0.05。3)、亚1 组和亚2 组患者残余尿量、最大尿流率、最大尿流率时逼尿肌压、最大逼尿肌压及顺应性，P值均<0.05。4)、亚1 组和亚2组不稳定膀胱率明显高于对照组。结论：II型糖尿病能加重前列腺增生患者膀胱功能障碍，及早控制血糖能减轻、延缓膀胱功能障碍。

英文摘要:

Objective:To investigate the changes of urodynamics on benign prostatic hyperplasia combined with type 2 diabetes mellitus, and to provide a reasonable and operative therapy scheme.Methods:From September 2010 to September 2013, 349 cases of benign prostatic hyperplasia were confirmed on pathological examination afte TURP in our hospital. 349 patients with BPH were divided into two groups，general BPH （control group, 158 cases）and BPH with type 2 diabetes mellitus that was divided into two groups, namely the fasting blood glucose ≤ 6.1 mmol/L (group 1 , 96 cases) and fasting blood glucose > 6.1 mmol/L (group 2 , 95 cases). The test results of urodynamics were compared with groups of patients.Results:1.Compared group 2 with control group, PVR, Q max, Pdet at Q max, Pdet Q max and BC had distinguished differences ( P< 0.05). 2.Compared group 1 with control group, PVR，Q max, Pdet at Q max, Pdet Q max and BC had distinguished differences ( P< 0.05) except PVR, BC when course < 5 year. 3.Compared group 2 with group 1, PVR, Q max, Pdet at Q max, Pdet Q max and BC had distinguished differences ( P< 0.05). 4. The rate of unstable bladder in group 1 and group 2 were significantly higher than that of the control group.Conclusion:The influence of Type 2 diabetes on the function of the bladder in BPH patients is significant. To control High blood sugar as soon as possible can reduce and delay the bladder dysfunction.

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