| 林鲁飞 麦笃雄 吴艳洪 卢维城 陈金妮.TnT-Hs和NSE在手足口病患儿中的表达水平及临床意义[J].,2014,14(24):4744-4746 |
| TnT-Hs和NSE在手足口病患儿中的表达水平及临床意义 |
| The Expression and Clinical Significance of TnT-Hs and NSE in Foot andMouth Disease in Children |
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| DOI： |
| 中文关键词: 心肌钙蛋白T 血清神经元特异性烯醇化酶 手足口病 |
| 英文关键词: Cardiac troponin T Serumneuron-specific enolase Foot and mouth disease |
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| 中文摘要: |
| 目的：探讨TnT-Hs和NSE 水平在手足口病患儿中的表达及临床意义。方法：选择我院2012 年6 月~2013 年6 月确诊为手
足口病的住院患儿68 例作为观察组，选择同期入院健康体检的68 例正常儿童作为对照组，对比两组心肌钙蛋白T（TnT-Hs）与
血清神经元特异性烯醇化酶（NSE）水平；并对观察组EV71 阳性患儿与阴性患儿TnT-Hs与NSE 水平进行比较。结果：①相比健
康对照组，观察组TnT-Hs 与NSE 水平均较高，差异有统计学意义（P＜0.01）。②EV71 阳性患儿46 例，阴性患儿22例，阳性患儿
相比阴性患儿TnT-Hs与NSE 水平较高，差异均有统计学意义（P＜ 0.05）。结论：Tn-T-Hs 和NSE 水平可反映手足口病患儿病情进
展变化，其可作为早期预测手足口病患儿心肌损害及脑损伤的依据及重症病例的预警指标。 |
| 英文摘要: |
| Objective:To discuss the expression and clinical significance of TnT-Hs and NSE of foot and mouth disease in
children.Methods:68 cases of hospitalized children who were diagnosed HFMD in our hospital in June 2012 - June 2013 were selected
as the observation group, and 68 normal healthy children at the same period of admission were selected as the control group,the cardiac
troponinT (TnT-Hs) and serum neuron-specific enolase (NSE) levels of two groups were compared.Results:① Compared with the
healthy control group, the TnT-Hs and NSE levels of observation group were higher, and the difference was statistically significant (P<0.
01). ② There were 46 cases of EV71 positive patients, and 22 cases negative. The TnT-Hs and NSE levels of the positive patients were
higher than those of negative patients, and the differences were statistically significant (P<0.05).Conclusion:The Tnt-Hs and NSE levels
may reflect the changes of disease progression of HFMD, it can be used as an early prediction for the myocardial damage and brain
damage in HFMD children and also as an early warning indicators for severe cases. |
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