| 邓春晖 张本金 吕有道 雷克竞 姚毅.生长激素治疗特发性矮小疗效观察及分析[J].,2014,14(23):4516-4518 |
| 生长激素治疗特发性矮小疗效观察及分析 |
| Curative Effect Observation and Analysis of Growth Hormone Treatment for Idiopathic Short |
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| DOI： |
| 中文关键词: 生长激素 特发性矮小 观察及分析 疗效 |
| 英文关键词: Growth hormone Idiopathic short Observation and analysis Curative effect |
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| 中文摘要: |
| 目的：探究生长激素对特发性矮小(idiopathic short, ISS）的作用及临床疗效。方法：在我院临床接受ISS治疗的病患中，随机
选取84 例作为研究对象。按照随机分组法把其分为观察组（44 例）和对照组（40 例）。对照组进行常规治疗。观察组每日睡前注
射生长激素0.16—0.20IU/kg。对比分析两组病患治疗后身高、身高标准差及生长速率情况。结果：对照组治疗后无明显增高现象，
而观察组增高现象显著。差异均有统计学意义（均P＜0.05）。观察组疗效优者占63.6%（28/44）,优良率为95.5%（42/44),均明显高
于对照组的35%（14/40），80%（32/40),差异均有统计学意义（均P＜0.05）。结论：生长激素用于治疗ISS 病患疗效显著，并能有效
改善ISS 病患身高、生长速率,安全性有保证,值得临床治疗广泛推荐。 |
| 英文摘要: |
| Objective:To explore the curative effect of growth hormone treatment for ISS.Methods:84 cases of ISS treated in our
hospital were randomly divided into two groups: observation group (44 cases) and control group (40 cases). The control group received
routine treatment while the observation group received daily injections of growth hormone 0.16-0.20 IU/kg. Standard deviation, growth
rate and height of two groups were analyzed.Results:No significant height increase was observed in control group, however patients in
observation group were heigher and the growth rate was significantly higher than that of control group (all P<0.05). Curative effect of
observation group accounted for 63.6%(28/44) and fine rate was 95.5%(42/44), which were notably higher than those in control group
[respectively 35% (14/40), 80% (32/40)]. The differences were statistically significant (all P<0.05).Conclusion:The growth hormone
used in the treatment of patients with ISS presents distinct curative effect , and can effectively improve the ISS patient’s height and
growth rate. Its security can be guaranteed and is worthy to be widely recommended as a clinical therapy. |
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