唐纪文 林秀娟 陈国胜 刘配芬 程小明.血清降钙素原、乳酸清除率及危重疾病评分对脓毒症预后的评估价值[J].,2014,14(22):4326-4328 |
血清降钙素原、乳酸清除率及危重疾病评分对脓毒症预后的评估价值 |
Evaluation Value of SerumProcalcitonin, Lactic Acid Clearance Rate andAcute Physiology and Chronic Health EvaluationⅡ to Sepsis |
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DOI: |
中文关键词: 血清降钙素原 乳酸清除率 危重疾病评分 脓毒症 |
英文关键词: Serumprocalcitonin Lactate clearance rate Critical illness score Sepsis |
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中文摘要: |
目的:探讨血清降钙素原(procalcitonin,PCT)、乳酸清除率及危重疾病评分(Acute Physiology and Chronic Health Evaluation
Ⅱ,APACHEⅡ)对脓毒症预后的评估价值。方法:选择2011 年2 月~2013 年2 月期间我院收治的脓毒症休克及严重脓毒症患者
92例,其中脓毒症休克37 例,严重脓毒症者55 例;存活60 例,死亡32 例。对本组患者血清PCT、乳酸清除率及APACHEⅡ进行
分析,探讨以上指标对其预后的评定价值。结果:①死亡组血清PCT、APACHEⅡ、乳酸分值均大于存活组,左心射血分数(Left
ventricular ejection fraction,LVEF)及早期乳酸清除率小于存活组,对比具有统计学意义(P<0.01 或P<0.05);② 脓毒性休克组血清
PCT、APACHEⅡ、乳酸分值均大于严重脓毒症组,LVEF 及早期乳酸清除率小于严重脓毒症组,对比具有统计学意义(P<0.01 或
P<0.05);③本组乳酸与APACHEⅡ呈正相关性(P<0.01),早期乳酸清除率与APACHEⅡ呈负相关性(P<0.01)。结论:PCT、乳酸清
除率及APACHEⅡ评分可以作为脓毒血症预后的有效评估指标,通过对PCT、乳酸清除率及APACHEⅡ评分监测以便尽早采取
积极的治疗措施,改善预后情况。 |
英文摘要: |
Objective:To explore the significance of serumprocalcitonin (PCT), lactate clearance rate and Acute Physiology and
Chronic Health Evaluation Ⅱ ( APACHE Ⅱ) in the evaluation of sepsis.Methods:92 patients with septic shock and severe sepsis were
selected in our hospital fromFebruary 2012 to February 2013, including37 cases of septic shock and 55 cases of severe sepsis patients; 60
cases survived, 32 cases died. The serum levels of PCT, lactate clearance rate and APACHE Ⅱ analysis, discussion of the assessment
value of above indexes on the prognosis.Results:① The serum levels of PCT, APACHE Ⅱ , lactate values of death group were greater
than the survival group, LVEF and the early lactate clearance rate is less than the survival group (P<0.01 or P<0.05); ② Septic shock
group serumPCT, APACHE Ⅱ scores, lactic acid more severe sepsis group, LVEF and early lactate clearance rate less than severe sepsis
group (P<0.01 or P<0.05); ③ The lactic acid and APACHE Ⅱ were positively correlated (P<0.01), the early lactate clearance rate was
negatively correlated with APACHE II (P <0.01).Conclusion:PCT, lactate clearance rate and APACHE Ⅱ can be used as an effective
evaluation index of sepsis prognosis, through the PCT, lactic acid clearance rate and APACHE Ⅱ monitoring so as to take active
treatment, improve the prognosis of the patients. |
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