Spleen hyperthyroidism caused by viral hepatitis and cirrhosis is a common clinical liver disease, it often leads to
enlarged spleen, excessive consumption of blood cells, bone marrow transplantation and other clinical syndrome, seriously influences the
anti-viral therapy against viral hepatitis. Currently, non-surgical treatment is difficult to control the enlargement of the spleen, and there
are no specific drugs available, result in bleeding by severe anemia and thrombocytopenia. Compared with non-surgical treatment, the
surgical and interventional treatment, including splenectomy, spleen resection, intervention (splenic artery embolization), is more direct
and exact, especially of splenectomy. However, splenectomy is harmful to the immune function, it makes people aware of the importance
of spleen-preserving, but there are still disputes on how to maximize the retention of the spleen and splenic function. Here, we would first
review the causes and mechanisms of hypersplenismin liver cirrhosis, then discuss the diagnostic criteria and treatment of hypersplenism,
thus provide a theoretical basis for hypersplenismstudy. |