文章摘要
谢渡江 周陵 李小波 张幼祥 王蓉 陈绍良.国产Amplatzer蘑菇伞介入治疗中老年动脉导管未闭的近中期疗效分析[J].,2014,14(19):3703-3705
国产Amplatzer蘑菇伞介入治疗中老年动脉导管未闭的近中期疗效分析
The Short and Intermediate TermEfficacy of Transcatheter Closureby Homemade Amplatzer MushroomOccluderof Patent Ductus Arteriosus for the Middle-aged or Geratic Patients
  
DOI:
中文关键词: 动脉导管未闭  介入治疗  中老年  近中期疗效  国产封堵器
英文关键词: Patent ductus arteriosus  Interventional therapy  Middle-aged patients  Short and intermediate term efficacy  Homemade occluder
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作者单位
谢渡江 周陵 李小波 张幼祥 王蓉 陈绍良 南京医科大学附属南京医院(南京市第一医院)心内科
南京医科大学附属南京医院(南京市第一医院)心血管超声科 
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中文摘要:
      目的:评价国产Amplatzer蘑菇伞介入治疗中老年动脉导管未闭(patent ductus arteriosus,PDA)的近中期临床疗效及安全性。 方法:选择2007 年1 月至2011 年12 月我院收治的32 例中老年PDA患者,经临床、心电图、X 线及经胸超声心动图(TTE)检查确 诊,均成功行介入治疗。术后行心电图、X线胸片、TTE 随访。结果:32例均1 次封堵成功,成功率100%。无重要并发症发生。随 访X线胸片显示肺血较术前减少,心胸比率不同程度缩小。术后48 小时(32 例)超声心动图显示左房内径(LAD)、左室舒张末内径 (LVDd)及肺动脉收缩压(PASP)较封堵前明显缩小(P<0.01);术后1、3、6 月(32 例)超声心动图随访显示LAD 及LVDd、PASP 进一 步缩小;术后1 年(30 例)、术后2年(20 例)、术后3 年(12 例)、术后4 年(5 例)超声心动图随访显示心脏大小及肺动脉收缩压恢复 正常。结论:国产Amplatzer蘑菇伞介入治疗中老年PDA 具有操作简单、创伤小、安全且技术成功率高、住院时间短等优点,近中 期疗效明确,并发症少。
英文摘要:
      Objective:To evaluate the short and intermediate term efficacy as well as safety of transcatheter closure by homemade Amplatzer mushroom occluder of patent ductus arteriosus in the treatment of middle-aged or geratic patients.Methods:32 cases with PDA who were confirmed by clinical manifestation, electrocardiogram (ECG), X-ray fluoroscopy, transthoracic color Doppler echocardiography (TTE) from January 2007 to December 2011 were selected and received the transcatheter occlusion. Then the follow-ups were conducted.Results:32 cases were all successfully occluded with the rate of 100%. In follow-ups, X-ray fluoroscopy showed pulmonary venous pleonaemia reduced and cardio-thoracic ration decreased. After 48 hours, the LAD, LVDd and PASP reduced obviously (P<0.01); after 1 year (30 cases), 2 years (20 cases), 3 years (12 cases) and 4 years (5 cases). There was no death, complication or therapy.Conclusion:Transcatheter closure of PDA in middle-aged or geratic patients using the homemade Amplatzer mushroom occluder was safety and efficacy with easy procedure, less complication, high successful rate and shorter hospitalization.
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