| 毕玉燕 姜翠凤 李维新 李静 李莎.妊娠期肝内胆汁淤积导致新生儿肺损伤的高危因素及干预对策[J].,2014,14(12):2309-2312 |
| 妊娠期肝内胆汁淤积导致新生儿肺损伤的高危因素及干预对策 |
| Risk Factors and Interventions of Neonatal Lung Injury Caused byIntrahepatic Cholestasis of Pregnancy |
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| DOI： |
| 中文关键词: 肝内胆汁淤积症综合症 新生儿肺损伤 危险因素 干预对策 |
| 英文关键词: Intrahepatic cholestasis syndrome Neonatal lung injury Risk factors Intervention Strategies |
| 基金项目:国家自然科学基金项目(81172201) |
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| 中文摘要: |
| 目的：探讨妊娠期肝内胆汁淤积症综合症所致新生儿肺损伤的危险因素，并采取相应的措施以提高临床治疗水平。方法：选
取2010 年1 月-2013 年1 月我院收治的70 例妊娠肝内胆汁淤积症综合症患者作为观察组，另选取同期接受体检的65 例正常晚
期妊娠妇女为对照组。分析新生儿肺损伤的相关因素。结果：妊娠肝内胆汁淤积症综合症所致新生儿肺损伤高危险因素有高雌激
素水平、机体免疫失衡、高微量元素硒、高总胆汁酸、高甘胆酸（p 均<0.05）。结论：妊娠肝内胆汁淤积症综合症所致新生儿肺损伤
的高危因素较多，临床上要积极采取措施，避免产后母婴并发症的发生。 |
| 英文摘要: |
| Objective:To investigate the risk factors of syndrome of intrahepatic cholestasis of pregnancy induced lung injury in
neonatal, and take corresponding measures in order to improve the level of clinical treatment.Methods:70 patients with neonatal lung
injury induced by intrahepatic cholestasis of pregnancy from January 2010 to January 2013 were selected as the observation group, and
another 65 pregnant women who were accepted the inspection at the same time were chosen to be the control group. Then the related
factors of neonatal lung injury were analyzed by regression.Results:The high risk factors of neonatal lung injury induced by intrahepatic
cholestasis of pregnancy were high estrogen levels, immune imbalances, high-selenium, high total bile acid, high cholyglycine (P<0.05).Conclusion:Many high risk factors are related to intrahepatic cholestasis of pregnancy induced neonatal lung injury syndrome. It is
suggested that the active measures should be taken to avoid the postpartumcomplications of maternal and infants. |
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