| 张丽琴1 邢昌赢2△ 解林花1 周惠1 季晓琪1.重症急性肾损伤患者经连续性肾脏替代治疗后肾功能恢复的影响因素[J].,2014,14(8):1490-1493 |
| 重症急性肾损伤患者经连续性肾脏替代治疗后肾功能恢复的影响因素 |
| Risk Factors of Renal function Recovery Among Patients of Severe AcuteKidney Injury with Continuous Renal Replacement Therapy |
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| DOI： |
| 中文关键词: 急性肾损伤（AKI） 连续性肾脏替代治疗（CRRT） 危险因素 |
| 英文关键词: Acute kidney injury(AKI) Continuous renal replacement therapy(CRRT) Risk factor |
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| 中文摘要: |
| 摘要目的：通过研究重症急性肾损伤患者经连续性肾脏替代治疗后肾功能恢复的影响因素，为重症急性肾损伤患者的诊治及预
后提供科学依据。方法：选取2009 年7 月至2013 年10 月本院住院且采用CRRT 治疗的284 例重症急性肾损伤患者，记录患者
的一般资料、APACHE Ⅱ评分、血液生化指标、伴随症状及肾功能预后情况，将预后情况和各影响因素进行Logistic 回归分析得出
影响肾功能恢复的影响因素。结果：284 例重症急性肾损伤患者中，肾功能恢复有89 例（31.33%）；肾功能恢复组的年龄、衰竭器官
数、APACHE Ⅱ评分、动脉血二氧化碳分压、合并慢性肾脏病率及合并严重基础疾病率均低于肾功能未恢复组，而平均动脉压和
血小板计数高于肾功能未恢复组（P<0.05），两组间合并机械通气率和合并少/ 无尿率无统计学差异（P>0.05）；衰竭器官数、APACHE
Ⅱ评分、合并严重基础疾病及AKI 分期为CRRT治疗重症急性肾损伤患者肾功能恢复的危险因素。结论：CRRT治疗重症急
性肾损伤的主要危险因素为衰竭器官数、APACHE Ⅱ评分、合并严重基础疾病及AKI分期。在临床治疗中，应正确评估病情，早期
及时采取CRRT 治疗，以提高生存率，促进肾脏功能恢复。 |
| 英文摘要: |
| ABSTRACT Objective：To analyze the risk factors of renal function recovery in patients with the severe acute kidney injury with
the method of continuous renal replacement so as to provide a scientific basis to the diagnosis, the treatment and the prognosis of the
disease. Methods：Choose 284 patients of severe acute kidney injury who was treated in our hospital from July 2009 to October 2013,
recoding each patient's general data, APACHE Ⅱ score, blood biochemical indicators, symptoms and renal function prognosis, then get
the risk factors of renal function recovery by Logistic regression analysis of prognosis and factors.Results： Among 284 patients, 89
patients' renal function recovered (31.33%); the age, number of failure organs, APACHE Ⅱ score, arterial blood of CO2 partial pressure,
the rate of chronic kidney disease and the rate of severe basic diseases of patients whose renal function recovered are lower than patients
whose renal function unrecovered (P<0.05), while the rate of mechanical ventilation and little/no urine between two groups have no
statistical difference (P>0.05). The number of failure organs, APACHE Ⅱ score, the rate of severe basic diseases and AKI stage are risk
factors of renal function recovery among patients of severe acute kidney injury with continuous renal replacement therapy.
Conclusion：The risk factors of renal function recovery among patients of severe acute kidney injury with continuous renal replacement therapy are
number of failure organs, APACHE Ⅱ score, the rate of severe basic diseases and AKI stage. In the clinical treatment, we should assess
the illness correctly and take CRRT treatment early and timely to improve the survival rate and promote the recovery of kidney function. |
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