| 李乃侠 韩玉惠 郑德泉 钟耀艺 吴欣宇.血栓通对急性脑梗塞患者血清D- 二聚体和超敏C 反应蛋白的作用[J].,2014,14(7):1304-1307 |
| 血栓通对急性脑梗塞患者血清D- 二聚体和超敏C 反应蛋白的作用 |
| Effect of Xueshuantong on SerumD-dimer and High Sensitivity C-reactiveProtein in Patients with Actue Cerebral Infarction |
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| DOI： |
| 中文关键词: 急性脑梗死 血栓通 D- 二聚体 超敏C- 反应蛋白 |
| 英文关键词: Acute cerebral infarction Xueshuantong D-dimer High sensitivity C-reactive protein |
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| 中文摘要: |
| 目的：观察血栓通对急性脑梗死(actue cerebral infarction, ACI) 患者血清D- 二聚体和超敏C 反应蛋白(high sensitivity
C-reactive protein, hs-CRP)水平的影响。方法：将68 例ACI患者随机分为观察组和对照组。两组进行常规治疗，观察组加用血栓
通0.5 g/d，静滴。于治疗前、治疗后3 d、7 d和14 d 检测患者血清D- 二聚体和hs-CRP 浓度变化，比较两组治疗前后改良爱丁堡-
斯堪的纳维亚神经功能评分(MESSS)及日常生活能力Barthel指数(BI)的变化。结果：观察组在治疗后3 d、7 d和14 d，血清D- 二
聚体和hs-CRP浓度较对照组明显降低(P < 0.05)，MESSS 和BI评分在治疗后7 d和14 d较对照组明显改善(P < 0.05)。观察组的
显效率和总有效率高于对照组(P < 0.05)。结论：血栓通可降低ACI患者血清D- 二聚体和hs-CRP水平，改善神经功能，是一种有
效治疗急性脑梗塞的方法。 |
| 英文摘要: |
| Objective:To observe the effect of xueshuangtong on serumD-dimer and high sensitivity C-reactive protein in patients
with ACI.Methods: Sixty-eight patients with ACI were randomly divided into two groups. One group received conventional treatment
(control group) and the other received additional intravenous drip 0.5 g of xueshuantong per day besides conventional medications
(treatment group). Serum concentrations of D-dimer and hs-CRP in the two groups were measured before the treatment and on 3 rd, 7 th
and 14 th day respectively after treatment.Results:Compared with control group, the serum levels of D-dimer and hs-CRP in treatment
group decreased significantly on the 3rd, 7th and 14th day after treatment (P < 0.05), while scores of MESSS and BI in treatment group
improved obviously on 7 th and 14 th day after treatment (P < 0.05). The markedly effective rate and the total effective rate of treatment
group were significantly than those of control group (P < 0.05).Conclusion:Xueshuangtong may reduce serum levels of D-dimer and
hs-CRP and have neurprotection role. The results showed that Xueshuangtong may represent an effective treatment of ACI. |
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