| 蒙果 李鸣皋 韩磊 杨业兵 赵鑫.酒石酸唑吡坦对非器质性失眠症患者Actigraphy检测指标的影响[J].,2014,14(7):1294-1296 |
| 酒石酸唑吡坦对非器质性失眠症患者Actigraphy检测指标的影响 |
| Effect of Zolpidem Tartrate on Actigraphy Parametersin Patients with Insomnia |
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| DOI： |
| 中文关键词: 失眠症 酒石酸唑吡坦 体动记录仪 睡眠障碍 |
| 英文关键词: nsomnia Zolpidemtartrate Actigraphy Sleep disorder |
| 基金项目:全军后勤重大基金项目（AHJ2011Z001） |
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| 中文摘要: |
| 目的：应用Actigraphy仪检测酒石酸唑吡坦对非器质性失眠患者睡眠质量的影响。方法：选择非器质性失眠症患者36 例，
实验第二晚给予10 mg酒石酸唑吡坦,实验第一晚和第四晚采用Actigraph 仪监测，观察用药后Actigraph 指标的变化。同时设置
正常对照组24 名，进行基础Actigraph 监测。结果：失眠组患者服用酒石酸唑吡坦后，夜间Actigraphy检测显示实际觉醒时间
(AWT) 、睡眠潜入期(SL) 、平均每次觉醒时间(MWB T) 与服药前相比，显著缩短( P < 0.01)；睡眠效率(SE) 、平均静息状态时长
(MLI) 与服药前相比，显著提高( P < 0.01) ，同时反映身体活动的参数平均活动分数(MAS) 和睡眠总体破碎程度的割裂指数( FI)
与对照组相比，显著降低( P < 0.05)。结论：酒石酸唑吡坦能明显改善非器质性失眠患者睡眠，在非器质性失眠症的诊断治疗中
Actigraphy仪是一种有效、便捷的方法。 |
| 英文摘要: |
| Objective:To investigate the effects of Zolpidemtartrate on sleep quality of patients with functional insomnia tested by
Actigraphy sleep instrument.Methods:All the patients received 10 mg Zolpidem tartrate before sleep on the second night, and actigraphy
sleep instrument was employed for 36 patients with insomnia on the first night and the fourth night, obtaining changes of Actigraphy
parameters. Another 24 participants without insomnia were recruited as the control group and tested by Actigraphy sleep instrument. Results:Compared with the parameters before treatment of Zolpidem tartrate, many parameters changed significantly, including reduced
actual wake time, sleep latency, mean wake bout time (P < 0.01), and improved sleep efficiency, mean length immobility (P < 0.01), and
reduced mean activity score, fragmentation index (P < 0.05).Conclusion:Zolpidem tartrate could significantly improve sleep quality of
patients with functional insomnia, and Actigraphy sleep instrument was an effective and convenient tool in the diagnosis and treatment of
patients with functional insomnia. |
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