文章摘要
齐瑞兆李志伟张培瑞洪智贤余灵祥肖朝晖赵新张绍庚张克明△.原发性肝癌患者术后两种营养支持的疗效对比及对免疫功能 的影响研究[J].,2014,14(5):888-891
原发性肝癌患者术后两种营养支持的疗效对比及对免疫功能 的影响研究
Comparison of Two Kinds of Nutritional Support on Efficacy and ImmuneFunction and Impact for HCC Patients
  
DOI:
中文关键词: 原发性肝癌  肠内营养  肠外营养  肝部分切除术  免疫功能
英文关键词: Primary liver cancer  Enteral nutrition  Parenteral nutrition  Partial hepatectomy  Immune function
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齐瑞兆李志伟张培瑞洪智贤余灵祥肖朝晖赵新张绍庚张克明△ 解放军第302 医院肝胆外科一中心 
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中文摘要:
      摘要目的:研究原发性肝癌患者术后两种营养支持的疗效及对免疫功能的影响。方法:病例选自2010 年10 月至2012 年11 月 在我院就诊治疗的90 例经诊断为原发性肝癌并进行肝部分切除的患者,随机分为EN 组和PN组,每组各45 例,分别进行肠内 和肠外营养支持治疗,观察术前及术后患者的营养状况、住院时间、肠道功能恢复时间、并发症情况及免疫功能的变化,经统计学 处理,探讨两种不同营养支持疗法的临床疗效及对免疫功能的影响。结果:相对于PN 组,EN 组患者术后营养明显改善,胃肠道功 能恢复相对较快,免疫功能明显提高,术后并发症明显减少,且P<0.05。差异具有统计学意义。结论:早期EN 比PN 更能改善肝 癌病人术后肠道功能及营养状况,降低术后并发症,提高患者的免疫功能,有利于患者术后恢复。
英文摘要:
      ABSTRACT Objective:To study two kinds of nutritional support for primary liver cancer patients, and its effect on immune function. Methods:90 cases of primary liver cancer with underwent liver resection in our hospital from October 2010 to November 2012 were selected, and were randomly divided into EN group and PN group (n = 45 patients), which were treated by enteral and parenteral nutrition therapy, respectively. Nutritional status, length of stay, intestinal function recovery time, complications and changes in immune function of patients were observed before and after treatment. The clinical effects of two different nutritional support efficacy and their effects on immune function were analyzed statistically. Results:Compared to PN group, postoperative nutrition was significantly improved, the recovery of gastrointestinal function was relatively rapid, immune function was significantly improved, postoperative complications was reduced significantly in EN group (P <0.05, the difference had statistically significance). Conclusion:In the Early period, EN is better for improving postoperative bowel function and nutritional status, reducing complications and improving the patient's immune function, helping patients recover than PN.
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