| ABSTRACT Objective:To investigate the factors influencing systemic lupus erythematosus (SLE) with low triiodothyronine (T3)
syndrome. Methods:30 SLE patients with low T3 syndrome, and 30 SLE patients with normal thyroid function were recruited.
Laboratory data including blood routine, C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), liver function, renal function,
serum complement C3, serum complement C4, Urine protein quantification in 24 hours and clinical presentations were collected, and
SLEDAI scores were assessed. The data were analyzed by single and multiple factors Logistic regression analysis. Results:There were
significant differences on SLEDAI scores, red blood cell count, hemoglobin level, platelet count, serum complement C3 level, serum
albumin level, serum glutamate pyruvate transaminase level, urea level, urine protein quantification in 24 hours between the two groups
(P<0.05). SLEDAI scores (OR=2.194, 1.045~4.606, P=0.038), hemoglobin level (OR=0.719, 0.518~0.998, P=0.049), serum glutamate
pyruvate transaminase level(OR=2.417, 1.071~5.457, P=0.034), serumalbumin level(OR=0.313, 0.105~0.934, P=0.037) were considered
as the factors impacting SLE with low T3 syndrome. Conclusion:SLEDAI scores and serum glutamate pyruvate transaminase level are
the risk factors, while hemoglobin and serumalbumin level are the protective factors for SLE combined with low T3 syndrome. |
