| 盛文芳 洪斌 张政 罗勇 王韦.老年高血压患者的动态脉压与冠心病并发症及颈动脉粥样硬化的关系研究[J].,2014,14(3):461-463 |
| 老年高血压患者的动态脉压与冠心病并发症及颈动脉粥样硬化的关系研究 |
| Research on Relationship of Elderly Hypertensive Patientswith Ambulatory Pulse Pressure (PP) and Coronary Heart DiseaseComplications and Carotid Atherosclerosis |
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| DOI： |
| 中文关键词: 动态脉压(PP) 老年高血压 冠心病 颈动脉粥样硬化 |
| 英文关键词: Ambulatory pulse pressure(pp) Elderly hypertension Coronary heart disease Carotid atherosclerosis |
| 基金项目: |
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| 中文摘要: |
| 目的：探讨老年高血压患者的动态脉压(PP)与冠心病并发症及颈动脉粥样硬化的关系。方法：选取2010 年5 月至2013 年6
月在我院就诊的老年性高血压病患者328 例，168 例单纯性老年高血压患者设为高血压组，160例合并有冠心病的老年性高血压
患者设为高血压合并冠心病组。根据厚度（IMT）是否增大将高血压组分为IMT 增厚组94 例和IMT 正常组74 例。对动态血压及
颈动脉IMT 进行测定。结果：与高血压组相比，高血压合并冠心病组的24 hAPP、dPP、nPP 等指标以及24 hASBP、nSBP等指标均
显著提高；而24hADBP、dDBP、nDBP等指标则明显下降；高血压合并冠心病组24hA PP艹60 mmHg 的发生率为57.50%，明显高
于高血压组的39.29%；IMT 增厚组患者的24hA PP、dPP 及nPP 水平均明显高于IMT 正常组；艹60 mmHg 组共89 例，IMT 为
1.14± 0.23 mm，明显高于< 60 mmHg 组79 例的平均厚度0.93± 0.12 mm（P<0.05）。结论：老年高血压患者的动态脉压在冠心病
并发症及颈动脉粥样硬化预测方面具有显著的优越性。 |
| 英文摘要: |
| Objective:To investigate the relationship of elderly hypertensive patients with ambulatory pulse pressure (PP) and
coronary heart disease complications and carotid atherosclerosis.Methods:328 cases of elderly hypertensive patients in our hospital from
May 2010 to June 2013 were chosen as the research objects, the mere 168 cases of elderly patients with hypertension were set as the
hypertension group,and 160 cases of CHD were set as hypertension combining coronary heart disease group. The hypertension group
were divided into IMT thickening group of 94 cases and 74 cases of IMT normal group. Ambulatory blood pressure and carotid artery
IMT were measured.Results:Compared with the hypertension group, the 24 hAPP, dPP, nPP and 24hASBP, nSBP of Hypertension
combining coronary heart disease group were significantly improved, while the 24 hADBP, dDBP, nDBP were obviously decreased;The
incidence of 24 hA PP≥ 60 mm Hg in hypertension combining coronary heart disease group was 57.50%, significantly higher than that
39.29%in hypertension group; the 24hAPP, dPP and nPP levels of IMT thickening group were significantly higher than the IMT normal
group; there were 89 cases of patients in ≥ 60 mmHg group, the IMT was 1.14 ± 0.23mm,significantly higher than that 79 cases of
patients and 0.93± 0.12 mm in<60 mmHg group（P<0.05）.Conclusion:Dynamic pulse pressure in elderly hypertensive patients has
obvious superiority in the prediction of coronary heart disease complications and carotid atherosclerosis. |
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