| 刘福剀 关雪 杨昕蕾 陈剑锋 杨永良 梁重阳.不同周龄Balb/c小鼠脏器质量及其变化趋势分析[J].,2014,14(3):421-424 |
| 不同周龄Balb/c小鼠脏器质量及其变化趋势分析 |
| Measurement and Change Trend Analysis of Organ Weights inBalb/c Mice of Different Ages |
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| DOI： |
| 中文关键词: Balb/c 小鼠 脏器质量 脏器系数 |
| 英文关键词: Balb/c rat Organ weight Organ coefficient |
| 基金项目:国家自然科学基金青年基金项目(81202446) |
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| 中文摘要: |
| 目的：测定不同周龄Balb/c 小鼠主要脏器质量、脏器系数，并进行比较。方法：取120 只3 周龄、5 周龄、7 周龄的Balb/c 小
鼠，雌雄各半，精确测量小鼠体重和主要脏器质量，计算脏器系数。结果：①雌性与雄性Balb/c 小鼠脏器质量相比较：3 周龄时肝、
脾有显著差异（P＜0.05）；5 周龄时肝有非常显著差异（P＜0.01），脾、肺有显著差异（P＜0.05）；7 周龄时肝、肺及双肾有非常显著差
异（P＜0.01），心、脾有显著差异（P＜0.05）。②雌性与雄性Balb/c 小鼠脏器系数相比较：3周龄时肝、脾有显著差异（P＜0.05）；5 周
龄时肝、脾有非常显著差异（P＜0.01），膀胱有显著差异（P＜0.05）；7 周龄时肺、双肾有非常显著差异（P＜0.01），脾、膀胱有显著差
异（P＜0.05）。结论：随着周龄的增长，Balb/c雌、雄性小鼠之间，存在差异的脏器也在增多。 |
| 英文摘要: |
| Objective:To measure and compare the weight of main organs and the organ coefficient between male and female
Balb/c mice of different ages.Methods:20 male and 20 female Balb/c mice at the ages of 3 weeks, 5 weeks and 7 weeks (total 120 mice)
were used for the measurement of weight of main organs and organ coefficient.Results:1. Comparing the organ weight between female
and male Balb/c mice, significant difference (P<0.05) for liver or spleen of mice of 3 weeks old, distinct significant differences (P<0.01)
for liver and significant differences (P<0.05) for spleen or lungs of mice of 5 weeks old, distinct significant differences (P<0.01) for liver,
lungs or double kidneys and significant differences (P<0.05) for heart or spleen of mice of 7 weeks old Balb/c were observed in the study.
2. Comparing the organ coefficient between female and male Balb/c mice, significant differences (P<0.05) for liver or spleen of mice of 3
weeks old, distinct significant differences (P<0.01) for liver or spleen and significant differences (P<0.05) for bladder of mice of 5 weeks
old; distinct significant differences (P<0.01) for lungs or double kidneys and significant differences (P<0.05) for spleen or bladder of mice
of 7 weeks old were observed in the study.Conclusion:As the growth of Balb/c mice, the difference of organs between female and male
mice is increasingly notable. |
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