文章摘要
陈英杰刘恒陈强梁宁震.化疗联合DC 和CIK方案治疗非小细胞肺癌的临床疗效观察[J].,2014,14(2):323-325
化疗联合DC 和CIK方案治疗非小细胞肺癌的临床疗效观察
The Clinical Effect Observation of Chemotherapy Combined with DC andCIK for the Treatment of Non-small Cell Lung Cancer
  
DOI:
中文关键词: 树突状细胞  细胞因子诱导的杀伤细胞  非小细胞肺癌  化疗
英文关键词: Dendritic cells (DC)  Cytokine-induced killer cells (CIK)  Non-small cell lung cancer  Chemotherapy
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作者单位
陈英杰刘恒陈强梁宁震 辽河油田第二职工医院肿瘤诊治中心 
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中文摘要:
      摘要目的:探讨化疗联合树突状细胞(DC)和细胞因子诱导的杀伤细胞(CIK)方案治疗非小细胞肺癌的临床疗效。方法:随机选取 2008年10月份-2011 年02 月份因非小细胞肺癌就诊于我院进行治疗的患者120 例,随机分为治疗组60 例患者(采用化疗联合 树突状细胞(DC)和细胞因子诱导的杀伤细胞(CIK)方案治疗),对照组60 例患者(采用常规化疗),统计两组患者的治疗效果以及 生活质量情况,并对结果进行统计分析。结果:治疗组患者治疗总有效率为68.4%,生活质量提高率为88.4%,明显好于与对照组, 经统计分析,P<0.05,差异存在显著性。结论:化疗联合树突状细胞(DC)和细胞因子诱导的杀伤细胞(CIK)方案治疗非小细胞肺癌 能够显著改善患者的生活质量,是治疗非小细胞肺癌的有效方法。
英文摘要:
      ABSTRACT Objective:To discuss the clinical effect of chemotherapy combined with dendritic cells (DC) and cytokine-induced killer cells (CIK) for the treatment of non-small cell lung cancer. Methods:From October, 2008 to February 2011, 120 patients with non-small cell lung cancer were randomly divided into treatment group (chemotherapy combined with dendritic cells (DC) and cytokine-induced killer cells (CIK) group, n=60)and control group (conventional chemotherapy group, n=60). We summarized the curative effect and the quality of life of patients and made a statistical analysis for the results.Results: In the treatment group, the total effective rate was 68.4%, the improvement rate of the quality of life was 88.4%. It was significantly better when compared with the control group. After the statistical analysis, P<0.05, there were significant differences. There was a significant difference in statistics. Conclusion:Chemotherapy combined with dendritic cells (DC) and cytokine-induced killer cells (CIK) for the treatment of non-small cell lung cancer can improve the quality of life for the patient. It is a effective method for the treatment of non-small cell lung cancer.
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