| 杜琼1 杨瑞1 朱开春2 玛依努尔·尼牙孜3△.阴道镜活检联合LEEP 术诊治宫颈病变的疗效分析[J].,2012,12(27):5353-5355 |
| 阴道镜活检联合LEEP 术诊治宫颈病变的疗效分析 |
| Analysis of the Effect of Diagnosis and Treatment of Cervical Lesion byColposcopy and Biopsy Combined with LEEP |
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| DOI： |
| 中文关键词: 阴道镜活检 宫颈环形电切术 宫颈病变 宫颈上皮内瘤变 |
| 英文关键词: Colposcopy and biopsy LEEP Cervical lesions CIN |
| 基金项目: |
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| 中文摘要: |
| 目的：探讨阴道镜活检联合宫颈环形电切术（LEEP 术）诊治宫颈病变的疗效。方法：对354 例宫颈病变患者在阴道镜下多点
活检后行LEEP 术治疗，并做病理组织学诊断，观察患者的手术时间、术中出血量及治疗效果，比较两种方法取材的病理组织学诊
断结果。结果：LEEP 术的平均手术时间长约6.76.7±3.5 min，术中出血量＜20 mL。2 个月后患者复查，成功率为93.8%（332/354
例），经二次手术全部治愈，并发症少。从病理组织学诊断结果来看，与LEEP 术相比，阴道镜下活检的炎症检出率高，宫颈上皮内
瘤变的检出率低，但差异均无显著统计学意义（P>0.05）。结论：根据阴道镜活检结果，针对性使用LEEP 术，密切随访，是诊治宫颈
病变的有效方法。 |
| 英文摘要: |
| Objective: To investigate the effect of diagnosis and treatment of cervical lesion by colposcopy and biopsy combined
with LEEP. Methods: 354 cases with cervical lesions were firstly treated with biopsy via colposcopy and then operated with LEEP. All
acquired tissue were sent for pathological diagnosis. The intraoperative, postoperative conditions and effects were observed. Results: The
average operative time of LEEP was 6.7 min with less blood loss. 2 months after operation, the surgical success rate was 93.8%, which
reached 100% after secondary surgery with less complications. Higher detection rate of inflammatory and lower detection rate of CINⅠ,
CINⅡ, CINⅢ via biopsy under colposcopy was observed than LEEP. But there was no significant difference (P>0.05). Conclusions:
Based on colposcopy and biopsy results, targeted use of LEEP was effective mean to diagnose and treat cervical lesions. |
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