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目的：探讨儿童急性淋巴细胞白血病分型对预后的影响，为临床治疗提供依据。方法：回顾性分析2007 年1 月~2008 年12 月我院收治的急性淋巴细胞白血病患儿32 例，比较不同分型的预后情况。结果：ALL-L1、ALL-L2 与ALL-L3 的首次诱导CR 率（X2=1.087，P＞0.05）、完全CR 率（X2=0.607，P＞0.05），差异无统计学意义；CR 的治疗时间（t=6.001，P＜0.05）、3 年生存率（X2=9. 458 ，P＜0.05），差异有统计学意义。T-ALL、B-ALL 的首次诱导CR 率（X2=8.891，P＜0.05）、达到CR 治疗时间（t=6.361，P＜0.05）、完全CR 率（X2=11.892，P＜0.05），差异有统计学意义。两型的3 年生存率（X2=1.536 ，P＞0.05），差异有统计学意义。B-ALL 中各型别首次诱导CR 率（X2=0.494，P＞0.05）和完全CR 率（X2=0.405，P＞0.05），差异统计学意义。B-ALL 中各型别达到CR 的治疗时间（t=7.007，P＜0.05）和3 年生存率（X2=6.609，P＜0.05），差异有统计学意义。结论：儿童急性白血病其预后与其分型有一定的相关性，因此临床治疗应结合患儿的分型进行个体化治疗。

英文摘要:

Objective: To analysis the somatotype of acute lymphoblastic leukemia influenced the prognostic, in order to provide basis for clinical treatment. Methods: A retrospective analysis of the clinical data for 36 patients with acute lymphoblastic leukemia in our hospital Jan. 2007 to Dec. 2010, to compare the prognostic. Results: The rate of first guide CR （X2=1.087, P＞0.05）and the rate of CR （X2=0.607, P＞0.05）of ALL-L1、ALL-L2 and ALL-L3 weren't statistical different significantly. The time of reached CR （t=6.001, P＜ 0.05）and the rate of 3-year-survied（X2=9.458, P＜0.05）of ALL-L1, ALL-L2 and ALL-L3 were statistical different significantly. The rate of first guide CR （X2=8.891, P＜0.05）, The time of reached CR （t=6.361，P＜0.05）, the rate of CR （X2=11.892，P＜0.05）of T-ALL, B-ALL were statistical different significantly. The rate of 3-year-survied（X2=1.536, P＞0.05）wasn't statistical different significantly. The rate of first guide CR （X2=0.494, P＞0.05）and the rate of CR （X2=0.405, P＞0.05）of the three of B-ALL weren't statistical different significantly. The time of reached CR （t=7.007, P＜0.05）and the rate of 3-year-survied （X2=6.609, P＜0.05）were statistical different significantly. Conclusion: The prognostic of ALL and the somatotype have relationship, so ALL were crued with individual factors for children.

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