| 金英兰陈曦董秀帅郭颖王京华△.巨幼细胞性贫血与脾大的临床相关性分析[J].,2012,12(25):4872-4874 |
| 巨幼细胞性贫血与脾大的临床相关性分析 |
| Analysis of Clinical Correlation between Megaloblastic Anemiaand Splenomegaly |
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| DOI： |
| 中文关键词: 巨幼细胞性贫血 脾脏 脾大 |
| 英文关键词: Megaloblastic anemia Spleen Splenomegaly |
| 基金项目: |
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| 中文摘要: |
| 目的：分析巨幼细胞性贫血脾肿大的超声表现及临床结果的相关性。方法：①选择2008 年至2011 年在哈尔滨医科大学第
二临床医院血液内科住院的巨幼细胞性贫血患者239 例。②按贫血程度将患者设为重度贫血组108 例（血红蛋白>30 g/L）；中度
贫血组78 例（血红蛋白>60 g/L）；轻度贫血组53 例（血红蛋白>90 g/L）。③超声检查显示脾厚度超过4 cm 或长度超过8 cm，最
大长径超过11 cm 以及左肋缘下探及脾，均可判定为脾大。④率的资料比较采用卡方检验，相关性分析采用Pearson 相关。结果：
对不同贫血程度的脾大发生率进行比较分析，采用卡方检验（x2=22.873，P<0.01）。贫血程度与脾大进行Pearson 相关性分析（r＝
0.309，P<0.01）。结论：①巨幼细胞性贫血可导致脾肿大。②脾大与贫血程度有关系。 |
| 英文摘要: |
| Objective: To analyze the correlation between clinical outcome and splenomegaly in megaloblastic anemia patients.
Methods: ① 239 patients with megaloblastic anemia were admitted who entered the Department of Hematology, the Second Affiliated
Hospital of Harbin Medical University from 2008 to 2011. ② These patients were divided into three groups according to the degree of
anemia: 108 patients with severe anemia (hemoglobin>30 g/L), 78 patients with moderate anemia (hemoglobin>60 g/L) and 53 patients
with mild anemia (hemoglobin>90 g/L). ③It was judged as splenomegaly that spleen was thicker than 4 cm, or longer than 8 cm, or the
major diameter of spleen was more than 11 cm by ultrasonic inspection. Splenomegaly was also decided when it could be touched along
the ribs.④Comparative analysis of the rate was made using x2, and relevance analysis was carried out by Pearson's correlation coefficient.
Results: x2 was used to compare the different incidence of splenomegaly of patients with different degree of anemia. (x2=22.873, P <
0.01). Pearson's correlation coefficient was used to evaluated the relationship between splenomegaly and degree of anemia. (r=0.309, P <
0.01). Conclusion:①Megaloblastic anemia could contribute to splenomegaly. ②The degree of anemia was involved in splenomegaly. |
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