| 高鹏1 胡立勇1 钱钰2 徐晨3.噬菌体抗体库筛选技术[J].,2012,12(23):4577-4583 |
| 噬菌体抗体库筛选技术 |
| Screening Isolates from Antibody Phage-display Libraries |
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| DOI： |
| 中文关键词: 噬菌体展示 抗体库 筛选技术 数据管理 |
| 英文关键词: Phage display Antibody library Screening technology Data management |
| 基金项目: |
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| 摘要点击次数: 959 |
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| 中文摘要: |
| 在过去的20 年中，噬菌体抗体库筛选技术被广泛的应用于抗体筛选、疾病治疗，临床诊断以及基础研究之中。在该技术的
应用过程中，快速有效的筛选出最适合的单克隆抗体并进行可靠和高效的数据管理和分析是十分重要的。文中总结了近年来噬
菌体抗体库的高通量筛选方法并且对数据管理做了简要介绍。 |
| 英文摘要: |
| For almost 20 years, phage display antibody (Ab) libraries screening have been widely used in antibody screen,
clinical diagnostic, treatment of disease and basic research areas. Rapid identification of the autofit monoclonal antibody, and reliable and
efficient data management and analysis are very important in the application of this technology. This review described reported methods
for high-throughput screening of antibody phage-display libraries and further more gave a brief introduction to data management. |
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