| 丁春梅1 陈史蓉1 刘荣辉1 张代富2 郭冀珍3.血浆B 型脑钠肽对急性冠脉综合征的病情影响及预后评估[J].,2012,12(22):4324-4326 |
| 血浆B 型脑钠肽对急性冠脉综合征的病情影响及预后评估 |
| Plasma B-Type Natriuretic Peptide Role for Evaluation of PathogeneticCondition and Outcome of Acute Coronary Syndrome |
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| DOI： |
| 中文关键词: 急性冠脉综合征 B 型脑钠肽 病情 预后 |
| 英文关键词: Acute Coronary Syndrome B-Type Natriuretic Peptide Pathogenetic Condition Outcome |
| 基金项目:陕西师范大学思想政治教育研究项目（SZYB11001） |
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| 中文摘要: |
| 目的：探讨血浆B 型脑钠肽（BNP）对急性冠脉综合征的病情影响及预后评估的作用，为临床实践提供参考。方法：分别对30
例健康体检者（对照组）和81 例ACS 患者（观察组）检测其入院24 小时内的血浆BNP 浓度，并在住院一周内行冠状动脉造影术，
检查病变的冠脉支数。结果：观察组的血浆BNP 浓度高于对照（P＜0.01），病变动脉支数与BNP 水平呈正相关（P＜0.01）。结论：
BNP 是急性冠脉综合征发病的重要因素，其水平高低可反映病情的严重程度，是预测病情和预后的重要指标。临床上应有效的监
测BNP 水平，对正确诊断和有效治疗急性冠脉综合征具有重要的意义。 |
| 英文摘要: |
| Objective: To study the role of plasma B-type natriuretic peptide to evaluate the pathogenetic condition and outcome
of acute coronary syndrome. Methods: 81 patients with ACS (observation group) and 30 health examination persons (controlling group)
were enrolled in this study. Plasma levels of BNP were detected in 24 hours after hospitalization and coronary angiography were
performed for detecting the affected coronary arteries in a week. Results: Plasma levels of BNP of the observation group were higher than
those of the controlling group （P＜0.01）. The correlation was positive between the number of affected coronary arteries and the levels of
BNP（P＜0.01）. Conclusion: BNP was an important factor in the pathogenesy of ACS; the levels of BNP may reflect the severity of ACS,
and BNP can be an important index to evaluate the pathogenetic condition and outcome. Monitoring the BNP level effectively in clinic
possesses is considered significant significance to diagnose exactly and reasonable treatment for acute coronary syndrome. |
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