| 艾永生1 桂文武2 孟江萍2 幸贵邦2 李恬2.HPV-DNA 亚型检测联合液基细胞学对宫颈癌
筛查的临床价值[J].,2012,12(22):4284-4287 |
| HPV-DNA 亚型检测联合液基细胞学对宫颈癌
筛查的临床价值 |
| Types of HPV-DNA Testing Combined with Liquid-Based Cytologyfor Cervical Cancer Screening Clinical Value |
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| DOI： |
| 中文关键词: 人乳头瘤病毒 液基细胞学 宫颈癌 |
| 英文关键词: Human papillomavirus Liquid-based cytology Cervical cancer |
| 基金项目: |
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| 摘要点击次数: 753 |
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| 中文摘要: |
| 目的：探讨HPV-DNA 亚型检测联合液基细胞学对宫颈癌筛查的临床价值。方法：对自愿接受宫颈癌筛查的女性1462 例作
为研究对象，分别对其进行HPV-DNA 亚型检测以及液基细胞学的检查，对于出现阳性的患者进行病理组织学检查。结果：HPV＋
TCT 对宫颈癌早期病变以及癌变的检出率为69.67%明显高于HPV 检查的56.28%以及TCT 检查的63.89%（P＜0.05）；HPV＋
TCT 对CINⅠ、CINⅡ、CINⅢ、癌的检出率分别为91.67%，92.86%、91.67%以及100%。结论：采用HPV-DNA 亚型检测联合液基
细胞学对宫颈癌筛查，可明显提高其对癌前病变的检出率，是一种高效、简单的检测方法。 |
| 英文摘要: |
| Objective: To investigate the subtypes of HPV-DNA testing combined with liquid-based cytology for cervical cancer
screening clinical value. Methods: voluntary acceptance of women 1462 cases of cervical cancer screening as a research object, respectively,
its subtype HPV-DNA testing and liquid-based cytology examination, the patients were positive for histopathological examination.
Results: HPV + TCT cervical cancer early lesions and cancer detection rate was 69.67% higher than HPV examination 56.28% and TCT
examination of 63.89% (P <0.05); HPV + TCT for CIN Ⅰ, CIN Ⅱ, CIN Ⅲ, cancer detection rate were 91.67%, 92.86%, 91.67% and
100%. Conclusion:The detection of HPV-DNA subtypes combined liquid-based cytology for cervical cancer screening, can significantly
improve the detection rate of precancerous lesions, is an efficient and simple detection method. |
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