| 龚婷1,2 贾素洁1 张毕奎1,2.内皮祖细胞生物学特性及其进展[J].,2012,12(21):4193-4196 |
| 内皮祖细胞生物学特性及其进展 |
| Biological Characteristics of Endothelial Progenitor Cells and ItsAdvancement |
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| DOI： |
| 中文关键词: 内皮祖细胞 血管内皮生长因子 细胞动员 细胞分化 细胞归巢 |
| 英文关键词: Endothelial progenitor cells(EPCs) Vein endothelial growth factors receptor (VEGF) Cell mobilization Cell differentiation Cell homing |
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| 中文摘要: |
| 内皮祖细胞( Endothelial Progenitor Cells, EPCs)是血管内皮细胞的前体细胞，即能分化为成熟血管内皮细胞的祖细胞。随着
对EPCs 功能和影响其分化、生存、归巢和组织分布因素的了解，EPCs 作为临床诊断、预后判断和治疗方法将有广阔的前景。本文
就EPCs 的的来源，EPCs 的分离、培养、鉴定，EPCs 的表面标志，EPCs 的动员、分化和归巢等生物学特性及其进展展开综述。 |
| 英文摘要: |
| Endothelial progenitor cells (EPCs) are precursors of endothelial cells, which are able to differentiate into mature
endothelial cells. Studies are needed to increase more detailed understanding on the mechanisms of EPCs differentiation, survival,
homing and distribution of the tissue. The human EPCs has potential to be used as diagnostic and prognostic or therapeutic tools in the
future. This paper reviewed the biological characteristics and its advancement of EPCs, which including separation, culture and identification,
surface marker, mobilization, differentiation and homing. |
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